Evidence map›Paper›PMID 27921051›Full record

ArticleACG case reports journal2016

Systemic Mastocytosis Causing Refractory Pruritus in a Liver Disease Patient.

Naga S Addepally, Jagpal S Klair, Mohit Girotra, Johnny Jones, Farshad Aduli

Open access · diamondAbstract readCase Reports
In one paragraph

Article in ACG case reports journal, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Mastocytosis: from a Molecular Point of View.Clinical reviews in allergy & immunology · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Naga S AddepallyDepartment of Internal Medicine, University of Arkansas for Medical Sciences, Little Rock, AR.
Jagpal S KlairDepartment of Internal Medicine, University of Arkansas for Medical Sciences, Little Rock, AR.
Mohit GirotraDivision of Gastroenterology and Hepatology, University of Arkansas for Medical Sciences, Little Rock, AR.
Johnny JonesDivision of Gastroenterology and Hepatology, University of Arkansas for Medical Sciences, Little Rock, AR.
Farshad AduliDivision of Gastroenterology and Hepatology, University of Arkansas for Medical Sciences, Little Rock, AR.
University of Arkansas for Medical Sciences · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Systemic mastocytosis (SM) results from clonal, neoplastic proliferation of abnormal mast cells. Patients become susceptible to itching, urticaria, and anaphylactic shock, which occurs due to histamine release from mast cells. SM may coexist alongside other systemic diseases, thus confounding the overall clinical presentation. We discuss a 23-year-old woman with refractory pruritus, which was initially attributed to primary sclerosing cholangitis but had a nonresponse to antihistaminics, ursodiol, and cholestyramine. Concurrent evaluation for polyarthritis revealed increased uptake in the proximal femur on a bone scan, and subsequent bone marrow biopsy revealed indolent SM, and this was understood to be the cause of her intractable pruritus.

Identifiers

PMID27921051
PMCPMC5126489
OpenAlexW2559750800

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.