Evidence map›Paper›PMID 27920986›Full record

ArticleIDCases2017

Fulminant ecchymosis as the initial manifestation of antiphospholipid syndrome (APS) triggered by respiratory syncytial virus (RSV) infection: A case report and review of the literature.

Jun Makino, Sanjana Koshy, Sonal Bajaj, Young-Gwang Jeong, David C Perlman

Open access · goldAbstract readCase Reports
In one paragraph

Article in IDCases, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 82% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Jun MakinoDivision of Infectious Diseases, Department of Medicine, Mount Sinai Beth Israel Medical Center, 19 Baird Hall, 16th Street at First Avenue, New York, NY 10003, USA.
Sanjana KoshyDivision of Infectious Diseases, Department of Medicine, Mount Sinai Beth Israel Medical Center, 19 Baird Hall, 16th Street at First Avenue, New York, NY 10003, USA.
Sonal BajajDivision of Infectious Diseases, Department of Medicine, Mount Sinai Beth Israel Medical Center, 19 Baird Hall, 16th Street at First Avenue, New York, NY 10003, USA.
Young-Gwang JeongDivision of Infectious Diseases, Department of Medicine, Mount Sinai Beth Israel Medical Center, 19 Baird Hall, 16th Street at First Avenue, New York, NY 10003, USA.
David C PerlmanDivision of Infectious Diseases, Department of Medicine, Mount Sinai Beth Israel Medical Center, 19 Baird Hall, 16th Street at First Avenue, New York, NY 10003, USA.
Mount Sinai Beth Israel · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We present a unique and informative instance of respiratory syncytial virus (RSV) infection associated with antiphospholipid syndrome (APS), and discuss this case in the context of the literature addressing the immunopathogenesis of APS associated with diverse infections. We describe the case of a 43-year-old man with no significant past medical history who presented with the acute onset of fever, hemoptysis, and extensive bullous, ecchymotic lesions in both lower extremities. Punch biopsy of the lesion demonstrated thrombotic vasculopathy. Further evaluation revealed serum antiphospholipid antibodies as well as a positive RSV PCR in a nasal swab specimen. Clinical manifestations, positive laboratory and pathological findings were strongly suggestive of APS associated with a recent RSV infection. When an infectious etiology is considered for APS, RSV should also be included in the differential diagnosis.

Indexed as

Anticardiolipin antibodies (aCL)Antiphospholipid syndrome (APS)Respiratory syncytial virus (RSV)

Identifiers

PMID27920986
PMCPMC5137331
OpenAlexW2552625587

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.