Evidence map›Paper›PMID 27920777›Full record

ArticleFrontiers in immunology2016

Physical Interaction of T Cells with Dendritic Cells Is Not Required for the Immunomodulatory Effects of the Edible Mushroom

Ruud H P Wilbers, Lotte B Westerhof, Jan van de Velde, Geert Smant, Debbie R van Raaij, Anton S M Sonnenberg, Jaap Bakker, Arjen Schots

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Potential of Mushroom Compounds as Immunomodulators in Cancer Immunotherapy: A Review.Evidence-based complementary and alternative medicine : eCAM · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Ruud H P WilbersPlant Sciences Group, Wageningen University and Research Centre , Wageningen , Netherlands.
Lotte B WesterhofPlant Sciences Group, Wageningen University and Research Centre , Wageningen , Netherlands.
Jan van de VeldePlant Sciences Group, Wageningen University and Research Centre , Wageningen , Netherlands.
Geert SmantPlant Sciences Group, Wageningen University and Research Centre , Wageningen , Netherlands.
Debbie R van RaaijPlant Sciences Group, Wageningen University and Research Centre , Wageningen , Netherlands.
Anton S M SonnenbergPlant Sciences Group, Wageningen University and Research Centre , Wageningen , Netherlands.
Jaap BakkerPlant Sciences Group, Wageningen University and Research Centre , Wageningen , Netherlands.
Arjen SchotsPlant Sciences Group, Wageningen University and Research Centre , Wageningen , Netherlands.
Wageningen University & Research · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mushrooms are well known for their immunomodulating capacities. However, little is known about how mushroom-stimulated dendritic cells (DCs) affect T cells. Therefore, we investigated the effect of mushroom compounds derived from seven edible mushroom species on DCs, their fate in DCs, and the effect of the mushroom-stimulated DCs on T cells. Each mushroom species stimulated DCs in a different manner as was revealed from the DC's cytokine response. Assessing DC maturation revealed that only one mushroom species,

Indexed as

dendritic cellimmunomodulationmushroomPAMPPRRT cell

Identifiers

PMID27920777
PMCPMC5118454
OpenAlexW2557033689

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.