ArticleCase reports in oncology
Metastatic Alveolar Soft Part Sarcoma Responsive to Pazopanib after Progression through Sunitinib and Bevacizumab: Two Cases.
Article in Case reports in oncology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed, 12 citations in OpenAlex.
- Imaging and Pathological Features of Alveolar Soft Part Sarcoma: Analysis of 16 Patients.The Indian journal of radiology & imaging · 2021Article
- Advanced alveolar soft part sarcoma responds to apatinib.Oncotarget · 2017Article
- Alveolar soft-part sarcoma of the mediastinum: A case report.SAGE open medical case reports · 2017Article
- Article
- Advanced Alveolar Soft Part Sarcoma Treated with Pazopanib over Three Years.Case reports in oncological medicine · 2017Article
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Alveolar soft part sarcoma (ASPS) is a rare soft tissue sarcoma with a propensity for lung metastases and indolent progression. ASPS is not responsive to chemotherapy, but there are case reports and small series describing benefit from drugs targeting the VEGF pathway. These drugs include sunitinib, cediranib and bevacizumab. There is no established second-line treatment for persons with ASPS progressing through first-line targeted therapy. We report two individuals with metastatic ASPS who obtained disease stabilization from sunitinib lasting over a year. After subsequent progression through sunitinib and second-line bevacizumab, both individuals again had disease response and subsequent stabilization from pazopanib.
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