Evidence map›Paper›PMID 27920651›Full record

ArticleCase reports in gastroenterology

Use of Direct-Acting Antivirals for the Treatment of Hepatitis C Virus-Associated Oral Lichen Planus: A Case Report.

Kenji Misaka, Takashi Kishimoto, Yuji Kawahigashi, Michio Sata, Yumiko Nagao

Abstract readCase Reports
In one paragraph

Article in Case reports in gastroenterology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Review
  2. Article
  3. Oral lichen planus and HCV infection.Autopsy & case reports · 2020
    Article
  4. HCV Extrahepatic Manifestations.Journal of clinical and translational hepatology · 2019
    Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Kenji MisakaMisaka Dental Clinic, Fukuoka, Japan.
Takashi KishimotoKishimoto Dental Clinic, Fukuoka, Japan.
Yuji KawahigashiDepartment of Organ System Interactions and Information, Saga Medical School, Saga, Japan.
Michio SataNishinihon Hospital, Kumamoto, Japan; Research Center for Innovative Cancer Therapy, Kurume University School of Medicine, Fukuoka, Japan.
Yumiko NagaoDepartment of Organ System Interactions and Information, Saga Medical School, Saga, Japan; Research Center for Innovative Cancer Therapy, Kurume University School of Medicine, Fukuoka, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hepatitis C virus (HCV) is frequently associated with various extrahepatic manifestations such as autoimmune features and immune complex deposit diseases. Oral lichen planus (OLP) is one of the representative extrahepatic manifestations of HCV infection. Direct-acting antivirals (DAA) are highly effective and safe for the eradication of HCV. However, there is a lack of information regarding the association between HCV-associated OLP and interferon (IFN)-free DAA therapy. Herein, we present the case of a 60-year-old female who was diagnosed with OLP during routine periodontal treatment by a dentist. The patient was referred for hepatitis C treatment using IFN-free DAA, which resulted in the improvement of the symptoms of OLP. This case represents the safety and efficacy of IFN-free DAAs in patients with HCV-associated OLP. However, long-term follow-up studies are required to elucidate the therapeutic effects of this therapy in these patients.

Indexed as

Direct-acting antiviralsExtrahepatic manifestationsHepatitis C virusInterferonOral lichen planus

Identifiers

PMID27920651
PMCPMC5121565

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.