ArticlePatient preference and adherence2016
Illness perceptions and stress: mediators between disease severity and psychological well-being and quality of life among patients with Crohn's disease.
Article in Patient preference and adherence, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 1 of them a synthesis that pooled it.
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Who cites it
38 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Self-compassion and psychological distress in chronic illness: A meta-analysis.British journal of health psychology · 2025Pooled it
- Impact of Upadacitinib Induction and Maintenance Therapy on Health-related Quality of Life, Fatigue, and Work Productivity in Patients with Moderately-to-severely Active Crohn's Disease.Journal of Crohn's & colitis · 2024Trial
- In-hospital psychological stress and post-hospital outcomes.Journal of health psychology · 2026Article
- Unmasking the Silent Struggle: The Impact of Psychological Distress and Social Support on Health-Related Quality of Life in Crohn's and Ulcerative Colitis.JMA journal · 2026Article
- Patient Identification of the most important outcomes in a gastrointestinal behavioral health program.Journal of patient-reported outcomes · 2026Article
- The Role of eHealth Literacy and Patient Adherence in Mediating Health Consciousness and Perceived Severity in Quality of Life Among Young Patients With Ischemic Heart Disease: Cross-Sectional Study.JMIR formative research · 2026Article
- Platelet-to-albumin ratio as an indicator for Crohn's disease activity and severity: a multicentre cross-sectional study.BMJ open · 2025Article
- Explaining the unknown: causal illness beliefs among people with epilepsy without identified cause.Epilepsy & behavior : E&B · 2025Article
- Mediating role of social support between stigma and social alienation in patients with inflammatory bowel disease: a cross-sectional study.Frontiers in psychology · 2025Article
- Investigating Patient Perspectives on Using eHealth Technologies for the Self-Management of Inflammatory Bowel Disease: Mixed Methods Study.Journal of medical Internet research · 2024Article
- Structural brain morphometry differences and similarities between young patients with Crohn's disease in remission and healthy young and old controls.Frontiers in neuroscience · 2024Article
- Exploring the Impact of Covid-19-Related Perceptions on Psychological Distress and Quality of Life in an International Gastrointestinal Cohort Over Time Guided by the Common Sense Model.Journal of clinical psychology in medical settings · 2023Article
- A qualitative investigation into the role of illness perceptions in endometriosis-related quality of life.Journal of health psychology · 2023Article
- Two-year trajectories of COVID-19 symptoms and their association with illness perception: A prospective cohort study in Amsterdam, the Netherlands.Influenza and other respiratory viruses · 2023Article
- Article
- Sexual Dysfunction in People with Multiple Sclerosis: The Role of Disease Severity, Illness Perception, and Depression.Journal of clinical medicine · 2023Article
- Is whole-body magnetic resonance imaging a source of anxiety in oncological patients?Cancer reports (Hoboken, N.J.) · 2023Article
- Extending the Common Sense Model to Explore the Impact of the Fear of COVID-19 on Quality of Life in an International Inflammatory Bowel Disease Cohort.Journal of clinical psychology in medical settings · 2022Article
- Health-related quality of life among Chinese patients with Crohn's disease: a cross-sectional survey using the EQ-5D-5L.Health and quality of life outcomes · 2022Article
- Understanding Perceived Stress in Adolescent Inflammatory Bowel Disease.Journal of the Canadian Association of Gastroenterology · 2022Article
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDisease severity, illness perceptions, coping strategies, stress, psychological well-being, and quality of life were reported to have close relationships. According to the Common Sense Model, illness perceptions and coping strategies could mediate the relationship between illness stimuli and illness outcomes such as psychological health and quality of life. Stress was also associated with the individual's disease severity, anxiety, depression, and quality of life.
objectivesThe study aimed to explore the influencing factors of illness outcomes, and to what extent illness perceptions, coping strategies, and stress mediate the relationship between disease severity and anxiety, and depression and quality of life.
methodsOur study included 159 patients with Crohn's disease who were attending a tertiary hospital outpatient clinic or who were hospitalized. Disease severity was measured with the Crohn's Disease Activity Index. Illness perceptions were measured with the Brief Illness Perceptions Questionnaire. Coping strategies were measured with the Carver Brief Coping Questionnaire. Stress was measured with the Perceived Stress Questionnaire. Anxiety and depression were measured with the Hospital Anxiety and Depression Scale. Quality of life was measured with the Inflammatory Bowel Disease Questionnaire.
resultsDisease severity, illness perceptions, maladaptive coping, stress, anxiety, depression and quality of life were significantly correlated with each other among patients with Crohn's disease. Using structural equation modeling to describe the inner relationship of the aforementioned variables, an excellent-fitted model was drawn. (
conclusionInterrelationships between disease stimuli, disease perceptions and management and disease outcomes could be found in patients with Crohn's disease. Illness perceptions and stress mediated an individual's disease severity and anxiety, depression and quality of life, while coping strategy was not an applicable mediator.
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