Evidence map›Paper›PMID 27920484›Full record

Trial reportWorld journal of gastroenterology2016

Psychological effects of colorectal cancer screening: Participants

Benedicte Kirkøen, Paula Berstad, Edoardo Botteri, Linn Bernklev, Badboni El-Safadi, Geir Hoff, Thomas de Lange, Tomm Bernklev

Abstract readComparative StudyRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in World journal of gastroenterology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Benedicte KirkøenBenedicte Kirkøen, Paula Berstad, Edoardo Botteri, Geir Hoff, Thomas de Lange, Department of bowel cancer screening, Cancer Registry of Norway, Majorstuen, 0304 Oslo, Norway.
Paula BerstadBenedicte Kirkøen, Paula Berstad, Edoardo Botteri, Geir Hoff, Thomas de Lange, Department of bowel cancer screening, Cancer Registry of Norway, Majorstuen, 0304 Oslo, Norway.
Edoardo BotteriBenedicte Kirkøen, Paula Berstad, Edoardo Botteri, Geir Hoff, Thomas de Lange, Department of bowel cancer screening, Cancer Registry of Norway, Majorstuen, 0304 Oslo, Norway.
Linn BernklevBenedicte Kirkøen, Paula Berstad, Edoardo Botteri, Geir Hoff, Thomas de Lange, Department of bowel cancer screening, Cancer Registry of Norway, Majorstuen, 0304 Oslo, Norway.
Badboni El-SafadiBenedicte Kirkøen, Paula Berstad, Edoardo Botteri, Geir Hoff, Thomas de Lange, Department of bowel cancer screening, Cancer Registry of Norway, Majorstuen, 0304 Oslo, Norway.
Geir HoffBenedicte Kirkøen, Paula Berstad, Edoardo Botteri, Geir Hoff, Thomas de Lange, Department of bowel cancer screening, Cancer Registry of Norway, Majorstuen, 0304 Oslo, Norway.
Thomas de LangeBenedicte Kirkøen, Paula Berstad, Edoardo Botteri, Geir Hoff, Thomas de Lange, Department of bowel cancer screening, Cancer Registry of Norway, Majorstuen, 0304 Oslo, Norway.
Tomm BernklevBenedicte Kirkøen, Paula Berstad, Edoardo Botteri, Geir Hoff, Thomas de Lange, Department of bowel cancer screening, Cancer Registry of Norway, Majorstuen, 0304 Oslo, Norway.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo investigate the possible long-term psychological harm of participating in colorectal cancer (CRC) screening in Norway.

methodsIn a prospective, randomized trial, 14294 participants (aged 50-74 years) were invited to either flexible sigmoidoscopy (FS) screening, or a faecal immunochemical test (FIT) (1:1). In total, 4422 screening participants (32%) completed the questionnaire, which consisted of the Hospital Anxiety and Depression Scale and the SF-12, a generic health-related quality of life (HRQOL) measurement, when invited to screening and one year after the invitation. A control group of 7650 individuals was invited to complete the questionnaire only, at baseline and one year after, and 1911 (25%) completed the questionnaires.

resultsReceiving a positive or negative screening result and participating in the two different screening modalities did not cause clinically relevant mean changes in anxiety, depression or HRQOL after one year. FS screening, but not FIT, was associated with an increased probability of being an anxiety case (score ≥ 8) at the one-year follow-up (5.6% of FS participants transitioned from being not anxious to anxious, while 3.0% experienced the reverse). This increase was moderately significantly different from the changes in the control group (in which the corresponding numbers were 4.8% and 4.5%, respectively),

conclusionMost individuals do not experience psychological effects of CRC screening participation after one year, while FS participation is associated with increased anxiety for a smaller group.

Indexed as

Occult BloodAgedAnxietyColorectal NeoplasmsDepressionEarly Detection of CancerFemaleHumansMaleMiddle AgedNorwayPredictive Value of TestsProspective StudiesQuality of LifeRisk FactorsSigmoidoscopyAnxietyColorectal cancer screeningControl groupFecal immunochemical testFlexible sigmoidoscopyHealth-related quality of life

Identifiers

PMID27920484
PMCPMC5116607

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.