Evidence map›Paper›PMID 27920473›Full record

ArticleWorld journal of gastroenterology2016

Na

Li-Hua Cao, Cheng-Cai Xia, Zhao-Chun Shi, Ning Wang, Zheng-Hua Gu, Li-Zhi Yu, Qi Wan, Wei De

Open access · hybridAbstract read
In one paragraph

Article in World journal of gastroenterology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 80% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Li-Hua CaoLi-Hua Cao, Ning Wang, Wei De, Department of Biochemistry and Molecular Biology, Nanjing Medical University, Nanjing 210029, Jiangsu Province, China.
Cheng-Cai XiaLi-Hua Cao, Ning Wang, Wei De, Department of Biochemistry and Molecular Biology, Nanjing Medical University, Nanjing 210029, Jiangsu Province, China.
Zhao-Chun ShiLi-Hua Cao, Ning Wang, Wei De, Department of Biochemistry and Molecular Biology, Nanjing Medical University, Nanjing 210029, Jiangsu Province, China.
Ning WangLi-Hua Cao, Ning Wang, Wei De, Department of Biochemistry and Molecular Biology, Nanjing Medical University, Nanjing 210029, Jiangsu Province, China.
Zheng-Hua GuLi-Hua Cao, Ning Wang, Wei De, Department of Biochemistry and Molecular Biology, Nanjing Medical University, Nanjing 210029, Jiangsu Province, China.
Li-Zhi YuLi-Hua Cao, Ning Wang, Wei De, Department of Biochemistry and Molecular Biology, Nanjing Medical University, Nanjing 210029, Jiangsu Province, China.
Qi WanLi-Hua Cao, Ning Wang, Wei De, Department of Biochemistry and Molecular Biology, Nanjing Medical University, Nanjing 210029, Jiangsu Province, China.
Wei DeLi-Hua Cao, Ning Wang, Wei De, Department of Biochemistry and Molecular Biology, Nanjing Medical University, Nanjing 210029, Jiangsu Province, China.
Nanjing Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo determine the expression and localization of the electrogenic Na

methodsThe rat pancreas from postnatal and embryos removed from the uterus of pregnant rats that had been sacrificed by CO

resultsThe results revealed the first peak of NBC1 expression at E18.5 and the second peak at P14. Meanwhile, the low NBC1 expression occurred at P7 and adult stages. Our results demonstrated, for the first time, the presence of NBC1 in the plasma membrane of β and α cells, as well as in the basolateral membrane of acinar cells of the rat pancreas at different stages of development.

conclusionThe data strongly suggests that NBC1 is diversely expressed in the pancreas at different developmental stages, where it may exert its functions in pancreatic development especially islet cell growth through HCO

Indexed as

Age FactorsAnimalsAnimals, NewbornBlotting, WesternFluorescent Antibody TechniqueGene Expression Regulation, DevelopmentalGestational AgeGlucagon-Secreting CellsInsulin-Secreting CellsMorphogenesisPancreasRats, Sprague-DawleyReverse Transcriptase Polymerase Chain ReactionRNA, MessengerSodium-Bicarbonate SymportersRNA, MessengerSlc4a4 protein, ratSodium-Bicarbonate SymportersImmunolocalizationNa+/HCO3- cotransporterPancreatic developmentα cellsβ cells

Identifiers

PMID27920473
PMCPMC5116596
OpenAlexW2549502309

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.