Evidence map›Paper›PMID 27920466›Full record

ArticleJournal of statistical computation and simulation2016

Joint Models for Multiple Longitudinal Processes and Time-to-event Outcome.

Lili Yang, Menggang Yu, Sujuan Gao

Abstract read
In one paragraph

Article in Journal of statistical computation and simulation, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
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  6. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Lili YangBiogen, 250 Binney Street, Cambridge, MA 02142.
Menggang YuDepartment of Biostatistics and Medical Informatics, University of Wisconsin.
Sujuan GaoDepartment of Biostatistics, School of Medicine, Indiana University.

Funding

Research Education ComponentP30AG010133 · NIA · INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS · PI SAYKIN, ANDREW J · 1991 to 2020
$37.3M
Selenium, other risk factors and cognitive decline in rural elderly ChineseR01AG019181 · NIA · INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS · PI GAO, SUJUAN · 2003 to 2014
$4.1M
Indianapolis Interventions and Practice Research Infrastructure ProgramR24MH080827 · NIMH · INDIANA UNIVERSITY INDIANAPOLIS · PI CALLAHAN, CHRISTOPHER M · 2008 to 2012
$3.1M
Longitudinal interactive vascular exposure and Alzheimer's DiseaseR01AG045350 · NIA · INDIANA UNIVERSITY INDIANAPOLIS · PI GAO, SUJUAN · 2014 to 2016
$925k
NIA NIH HHS P30 AG010133NIA NIH HHS R01 AG019181NIA NIH HHS R01 AG045350NIMH NIH HHS R24 MH080827
6 · The paper itself

Abstract

Joint models are statistical tools for estimating the association between time-to-event and longitudinal outcomes. One challenge to the application of joint models is its computational complexity. Common estimation methods for joint models include a two-stage method, Bayesian and maximum-likelihood methods. In this work, we consider joint models of a time-to-event outcome and multiple longitudinal processes and develop a maximum-likelihood estimation method using the expectation-maximization (EM) algorithm. We assess the performance of the proposed method via simulations and apply the methodology to a data set to determine the association between longitudinal systolic and diastolic blood pressure (BP) measures and time to coronary artery disease (CAD).

Indexed as

EM algorithmjoint modelsmultiple longitudinal outcomessimulationtime-to-event outcome

Identifiers

PMID27920466
PMCPMC5135019

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.