ArticleAnnals of Saudi medicine
Prevalence of IgG-mediated food intolerance among patients with allergic symptoms.
Article in Annals of Saudi medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05482997 (Athlete Whey Protein Sensitivity), which is not on this map. Cited by 17 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Athlete Whey Protein Sensitivity: Prevalence and Performance
Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it, 41 citations in OpenAlex.
- Food allergy in the Saudi population: trends, triggers, and strategies for care - a systematic review.Frontiers in public health · 2026Pooled it
- Immune dysfunction and food-specific IgG associated erosive oral lichen planus: a two-hit pathogenic model.Frontiers in immunology · 2026Article
- Immunoglobulin G-mediated food intolerance and metabolic syndrome influence the occurrence of reflux esophagitis inWorld journal of gastroenterology · 2024Article
- Mediation role of body mass index in the relationship between food-specific serum immunoglobulin G reactivity and colorectal adenomas in a Chinese population: a cross-sectional study.Therapeutic advances in gastroenterology · 2024Article
- Association between Food-Specific Immunoglobulin GBiomedicines · 2023Article
- Prevalence and Risk Factors for IgE and IgG Cow's Milk Protein Allergies in Saudi Arabia.Cureus · 2023Article
- Associations between food-specific IgG and health outcomes in an asymptomatic physical examination cohort.Nutrition & metabolism · 2022Article
- Predisposition of hypersensitivity in patients with exfoliative cheilitis.Journal of dental sciences · 2022Article
- Association betweenWorld journal of clinical cases · 2021Article
- Association of Migraine with Its Comorbidities and Food Specific Immunoglobulin G Antibodies and Inflammatory Cytokines: Cross-Sectional Clinical Research.Journal of pain research · 2021Article
- A free amino acid-based diet partially prevents symptoms of cow's milk allergy in mice after oral sensitization with whey.Immunity, inflammation and disease · 2020Article
- Serological investigation of IgG and IgE antibodies against food antigens in patients with inflammatory bowel disease.World journal of clinical cases · 2019Article
- The Clinical Application Value of Multiple Combination Food Intolerance Testing.Iranian journal of public health · 2019Article
- Use of a SelectedFoods (Basel, Switzerland) · 2019Article
- Review of Two Popular Eating Plans within the Multiple Sclerosis Community: Low Saturated Fat and Modified Paleolithic.Nutrients · 2019Review
- Cytokine Profile and Immunoglobulin E-mediated Serological Food Hypersensitivity in Patients With Irritable Bowel Syndrome With Diarrhea.Journal of neurogastroenterology and motility · 2018Article
- Biomarkers in oral immunotherapy.Journal of Zhejiang University. Science. BReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundFood intolerance mediated by food specific IgG antibodies has been implicated in a variety of disorders.
objectivesTo assess the prevalence of food specific IgG antibodies among patients clinically presenting with allergic symptoms lacking laboratory evidence of allergy.
designDescriptive retrospective cross-sectional study.
settingKing Khalid University Hospital, Riyadh between 2010-2015. PATIENTS AND
methodsPatients were screened for food specific IgG antibodies. All symptomatic patients lacking laboratory evidence of allergy who underwent food specific IgG testing during the study duration were included. MAIN OUTCOME MEASURE(S): Levels of IgG antibodies in patients with unidentified allergic symptoms.
resultsWe selected 71 patients with allergic symptoms lacking laboratory evidence of allergy. There were 49 female and 22 male patients mean age 38.8 (16.0) years. The majority (85.7%) had urticaria. The most frequently occurring food specific IgG antibodies were against cola nut in 80.3% of patients followed by yeast in 78.9%, wheat in 77.5%, red kidney bean in 71.8%, pea in 63.4%, corn in 62% and egg white in 62% of the patients. Compared with male patients, females harbored significantly higher food specific IgG antibodies for frequently occurring food materials, particularly against wheat (74% vs 25.5%; P < .0001), corn (77.3% vs 22.7%; P < .0001) and cola nut (71.9% vs 28.1%; P < .001). Patients aged less than 40 years had higher levels of food specific IgG against gliadin (P < .003), egg white (P < .03) and barley (P < .05) compared with older patients.
conclusionThe detection of a variety of food specific IgG antibodies among patients with allergic symptoms indicates a possible link to food intolerance allergy. Females are prone to develop food intolerance more than males. LIMITATIONS: Difficulty of comparison of results with previous studies because of lack of data. Follow-up studies could not be performed to assess the effects of elimination from the diet due to limited time allocated for this study.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.