Evidence map›Paper›PMID 27920395›Full record

ArticleThe American journal of tropical medicine and hygiene2017

Tetanus Immunity Gaps in Children 5-14 Years and Men ≥ 15 Years of Age Revealed by Integrated Disease Serosurveillance in Kenya, Tanzania, and Mozambique.

Heather M Scobie, Minal Patel, Diana Martin, Harran Mkocha, Sammy M Njenga, Maurice R Odiere, Sonia Pelletreau, Jeffrey W Priest, Ricardo Thompson, Kimberly Y Won and 1 more

Open access · bronzeAbstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in The American journal of tropical medicine and hygiene, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
2.9field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 33 citations in OpenAlex.

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  13. Seroepidemiology of tetanus in Hangzhou from 2009 to 2018.Human vaccines & immunotherapeutics · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 3 countries.

Heather M ScobieGlobal Immunization Division, Centers for Disease Control and Prevention, Atlanta, Georgia. hscobie@cdc.gov.
Minal PatelGlobal Immunization Division, Centers for Disease Control and Prevention, Atlanta, Georgia.
Diana MartinDivision of Parasitic Diseases and Malaria, Centers for Disease Control and Prevention, Atlanta, Georgia.
Harran MkochaKongwa Trachoma Project, Kongwa, Tanzania.
Sammy M NjengaEastern and Southern Africa Centre of International of Parasite Control, Kenya Medical Research Institute, Nairobi, Kenya.
Maurice R OdiereCentre for Global Health Research, Kenya Medical Research Institute, Kisumu, Kenya.
Sonia PelletreauDivision of Parasitic Diseases and Malaria, Centers for Disease Control and Prevention, Atlanta, Georgia.
Jeffrey W PriestDivision of Foodborne, Waterborne and Environmental Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia.
Ricardo ThompsonInstituto Nacional de Saúde, Maputo, Mozambique.
Kimberly Y WonDivision of Parasitic Diseases and Malaria, Centers for Disease Control and Prevention, Atlanta, Georgia.
Patrick J LammieDivision of Parasitic Diseases and Malaria, Centers for Disease Control and Prevention, Atlanta, Georgia.
Centers for Disease Control and Prevention · USDivision of Parasitic Diseases and Malaria · USKenya Medical Research Institute · KEInstituto Nacional de Saúde · MZWaterborne Environmental (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recent tetanus cases associated with male circumcision in Eastern and Southern Africa (ESA) prompted an examination of tetanus immunity by age and sex using multiplex serologic data from community surveys in three ESA countries during 2012-2013. Tetanus seroprotection was lower among children 5-14 years versus 1-4 years of age in Kenya (66% versus 90%) and Tanzania (66% versus 89%), but not in Mozambique (91% versus 88%), where children receive two booster doses in school. Among males ≥ 15 years of age, tetanus seroprotection was lower than females in Kenya (45% versus 96%), Tanzania (28% versus 94%), and Mozambique (64% versus 90%). Tetanus immunity from infant vaccination doses wanes over time, and only women of reproductive age routinely receive booster doses. To prevent immunity gaps in older children, adolescents, and adult men, a life-course vaccination strategy is needed to provide the three recommended tetanus booster doses.

Indexed as

AdolescentAdultAgedAged, 80 and overAge FactorsAntibodies, BacterialChildChild, PreschoolFemaleHumansInfantKenyaMaleMiddle AgedMozambiqueSerologic TestsAntibodies, Bacterial

Identifiers

PMID27920395
PMCPMC5303047
OpenAlexW2560404463

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.