ArticleThe Plant cell2016
The PLETHORA Gene Regulatory Network Guides Growth and Cell Differentiation in Arabidopsis Roots.
Article in The Plant cell, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 90 papers.
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Who cites it
90 citing papers in PubMed.
- Genome-Wide Analysis ofInternational journal of molecular sciences · 2026Article
- The multifaceted regulatory network of microRNA396: Orchestrating plant plasticity through coordinating development and various stresses.Journal of integrative plant biology · 2026Review
- PcabHLH58/PcabHLH151 regulates adventitious root development and nitrogen uptake in poplar.Nature communications · 2026Article
- A PLETHORA3/7 transcription factor shapes cucumber shoot architecture.The New phytologist · 2026Article
- Elucidating putative novel functions of the AINTEGUMENTA-LIKE 7 transcription factor in clubroot resistance in Arabidopsis.Plant molecular biology · 2026Article
- PLETHORA-autophagy axis activates organ regeneration through ROS modulation.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Integrating meristem initiation and floral fate control: towardFrontiers in plant science · 2026Review
- PLETHORAs shape Arabidopsis phyllotaxis through modulation of patterning robustness and accelerated inflorescence development.The New phytologist · 2026Article
- The ZAT14 family promotes cell death and regulates expansins to affect xylem formation and salt tolerance in Arabidopsis.The Plant cell · 2025Article
- Rational design of induced regeneration via somatic embryogenesis in the absence of exogenous phytohormones.The Plant cell · 2025Article
- Stimulatory Effect of Aluminum in Root Development ofInternational journal of molecular sciences · 2025Article
- Two deeply conserved non-coding sequences control PLETHORA1/2 expression and coordinate embryo and root development.Plant communications · 2025Article
- Stem cell regulators drive a G1 duration gradient during plant root development.Nature plants · 2025Article
- Out of the Niche: A Bird's-Eye View of the Molecular Networks Controlling Root Stem Cells.Plants (Basel, Switzerland) · 2025Review
- To grow or not to grow: the enigma of plant root growth dynamism.Plant molecular biology · 2025Review
- From peptides to patterning: Redox control of the master regulator PLT2 in Arabidopsis roots.Plant physiology · 2025Article
- Mapping Quantitative Trait Loci inPlants (Basel, Switzerland) · 2025Article
- A computational Evo-Devo approach for elucidating the roles of PLETHORA transcription factors in regulating root development.PloS one · 2025Article
- Crosstalk among plant hormone regulates the root development.Plant signaling & behavior · 2024Review
- ROS, an Important Plant Growth Regulator in Root Growth and Development: Functional Genes and Mechanism.Biology · 2024Review
30 more citing papers are in PubMed but not listed here.
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26 authors.
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Abstract
Organ formation in animals and plants relies on precise control of cell state transitions to turn stem cell daughters into fully differentiated cells. In plants, cells cannot rearrange due to shared cell walls. Thus, differentiation progression and the accompanying cell expansion must be tightly coordinated across tissues. PLETHORA (PLT) transcription factor gradients are unique in their ability to guide the progression of cell differentiation at different positions in the growing Arabidopsis thaliana root, which contrasts with well-described transcription factor gradients in animals specifying distinct cell fates within an essentially static context. To understand the output of the PLT gradient, we studied the gene set transcriptionally controlled by PLTs. Our work reveals how the PLT gradient can regulate cell state by region-specific induction of cell proliferation genes and repression of differentiation. Moreover, PLT targets include major patterning genes and autoregulatory feedback components, enforcing their role as master regulators of organ development.
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