Evidence map›Paper›PMID 27920181›Full record

ArticleThe Journal of infectious diseases2016

Chikungunya Virus Vaccines: Viral Vector-Based Approaches.

Katrin Ramsauer, Frédéric Tangy

Abstract read
In one paragraph

Article in The Journal of infectious diseases, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Trial
  2. Review
  3. Article
  4. Review
  5. Review
  6. Chikungunya Virus Vaccines: Platforms, Progress, and Challenges.Current topics in microbiology and immunology · 2022
    Review
  7. Current Status of Chikungunya in India.Frontiers in microbiology · 2021
    Review
  8. Review
  9. Vaccinia-based vaccines to biothreat and emerging viruses.Biotechnology & genetic engineering reviews · 2018
    Review
  10. Vaccines for epidemic infections and the role of CEPI.Human vaccines & immunotherapeutics · 2017
    Review
  11. Production of a Chikungunya Vaccine Using a CHO Cell and Attenuated Viral-Based Platform Technology.Molecular therapy : the journal of the American Society of Gene Therapy · 2017
    Article
  12. Development of Vaccines for Chikungunya Fever.The Journal of infectious diseases · 2016
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Katrin RamsauerThemis Bioscience, Vienna, Austria.
Frédéric TangyViral Genomics and Vaccination Unit, CNRS UMR 3569, Institut Pasteur, Paris, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In 2013, a major chikungunya virus (CHIKV) epidemic reached the Americas. In the past 2 years, >1.7 million people have been infected. In light of the current epidemic, with millions of people in North and South America at risk, efforts to rapidly develop effective vaccines have increased. Here, we focus on CHIKV vaccines that use viral-vector technologies. This group of vaccine candidates shares an ability to potently induce humoral and cellular immune responses by use of highly attenuated and safe vaccine backbones. So far, well-described vectors such as modified vaccinia virus Ankara, complex adenovirus, vesicular stomatitis virus, alphavirus-based chimeras, and measles vaccine Schwarz strain (MV/Schw) have been described as potential vaccines. We summarize here the recent data on these experimental vaccines, with a focus on the preclinical and clinical activities on the MV/Schw-based candidate, which is the first CHIKV-vectored vaccine that has completed a clinical trial.

Indexed as

AdenoviridaeAmericasAnimalsAntibodies, ViralChikungunya FeverChikungunya virusClinical Trials as TopicHumansImmunity, CellularImmunity, HumoralMeasles VaccineSouth AmericaVaccines, SyntheticVaccinia virusViral VaccinesVirusesAntibodies, ViralMeasles VaccineVaccines, SyntheticViral Vaccinesadenovirus vectorchikungunya virusmeasles virus vectorMVAvaccineviral vectorsVSV

Identifiers

PMID27920181
PMCPMC7107338

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.