ArticleBlood2017
Severe anemia early in life as a risk factor for sickle-cell kidney disease.
Article in Blood, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02373241 (Chronobiology and Chronopharmacology to Prevent Sickle Cell Kidney Disease), which is not on this map. Cited by 17 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Chronobiology and Chronopharmacology to Prevent Sickle Cell Kidney Disease
Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.
- Clinical and Genetic Predictors of Sickle Cell Nephropathy: A Global Systematic Review.Omics : a journal of integrative biology · 2025Pooled it
- Oral tetrahydrouridine and decitabine for non-cytotoxic epigenetic gene regulation in sickle cell disease: A randomized phase 1 study.PLoS medicine · 2017Trial
- Review
- Influence of hydroxyurea on tubular phosphate handling in sickle cell nephropathy.Hematology, transfusion and cell therapy · 2024Article
- Article
- Early Detection of Renal Complication in Children With Sickle Cell Disease: A Single Center Prospective Study.Cureus · 2024Article
- Sickle Cell Disease and CKD: An Update.American journal of nephrology · 2024Review
- Voxelotor and albuminuria in adults with sickle cell anaemia.British journal of haematology · 2022Article
- Longitudinal study of glomerular hyperfiltration and normalization of estimated glomerular filtration in adults with sickle cell disease.British journal of haematology · 2021Article
- Chronic organ injuries in children with sickle cell disease.Haematologica · 2021Article
- Investigations of Kidney Dysfunction-Related Gene Variants in Sickle Cell Disease Patients in Cameroon (Sub-Saharan Africa).Frontiers in genetics · 2021Article
- End points for sickle cell disease clinical trials: renal and cardiopulmonary, cure, and low-resource settings.Blood advances · 2019Article
- Targeting sickle cell disease root-cause pathophysiology with small molecules.Haematologica · 2019Review
- Hyperfiltration during early childhood precedes albuminuria in pediatric sickle cell nephropathy.American journal of hematology · 2019Article
- Fetal Hemoglobin Induction by Epigenetic Drugs.Seminars in hematology · 2018Review
- Oral carbon monoxide therapy in murine sickle cell disease: Beneficial effects on vaso-occlusion, inflammation and anemia.PloS one · 2018Article
- Evaluating risk factors for chronic kidney disease in pediatric patients with sickle cell anemia.Pediatric nephrology (Berlin, Germany) · 2017Observational
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 1 country.
Funding
Abstract
PubMed holds no abstract for this paper.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.