ArticleBMC complementary and alternative medicine2016
Chemical profiling, antimicrobial and insecticidal evaluations of Polygonum hydropiper L.
Article in BMC complementary and alternative medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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Who cites it
27 citing papers in PubMed.
- Saponins, the Unexplored Secondary Metabolites in Plant Defense: Opportunities in Integrated Pest Management.Plants (Basel, Switzerland) · 2025Review
- Natural Compounds as Antimicrobial Agents-2nd Edition.Antibiotics (Basel, Switzerland) · 2025Article
- Multiple benefits of herbs: Polygonaceae species in veterinary pharmacology and livestock nutrition.Veterinary and animal science · 2025Review
- Antibacterial activity ofFrontiers in plant science · 2025Article
- The genusHeliyon · 2024Review
- Fertility regulatory potential ofSaudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2022Article
- HPLC-DAD phenolics analysis, α-glucosidase, α-amylase inhibitory, molecular docking and nutritional profiles of Persicaria hydropiper L.BMC complementary medicine and therapies · 2022Article
- Antibacterial Potential of Extracts and Phytoconstituents Isolated fromPlants (Basel, Switzerland) · 2022Article
- Appraisal of selected ethnomedicinal plants as alternative therapies against onychomycosis: Evaluation of synergy and time-kill kinetics.Frontiers in pharmacology · 2022Article
- Antioxidant, Enzyme Inhibitory, and Molecular Docking Approaches to the Antidiabetic Potentials of Bioactive Compounds fromEvidence-based complementary and alternative medicine : eCAM · 2022Article
- The Potential Application of Green-Synthesized Metal Nanoparticles in Dentistry: A Comprehensive Review.Bioinorganic chemistry and applications · 2022Review
- Phytochemical Analysis,Evidence-based complementary and alternative medicine : eCAM · 2022Article
- Evaluation of Alpha-Amylase Inhibitory, Antioxidant, and Antimicrobial Potential and Phytochemical Contents ofPlants (Basel, Switzerland) · 2020Article
- GC-MS analysis of Myrtus communis extract and its antibacterial activity against Gram-positive bacteria.BMC complementary medicine and therapies · 2020Article
- Article
- Phytochemical Analysis, Ephedra Procera C. A. Mey. Mediated Green Synthesis of Silver Nanoparticles, Their Cytotoxic and Antimicrobial Potentials.Medicina (Kaunas, Lithuania) · 2019Article
- Current Challenges and Perspectives for the Use of Aqueous Plant Extracts in the Management of Bacterial Infections: The Case-Study ofInternational journal of molecular sciences · 2019Review
- Isolation of dihydrobenzofuran derivatives from ethnomedicinal species Polygonum barbatum as anticancer compounds.Biological research · 2019Article
- Bio-guided profiling and HPLC-DAD finger printing of Atriplex lasiantha Boiss.BMC complementary and alternative medicine · 2019Article
- Pharmacological Evaluation of Aldehydic-Pyrrolidinedione Against HCT-116, MDA-MB231, NIH/3T3, MCF-7 Cancer Cell Lines, Antioxidant and Enzyme Inhibition Studies.Drug design, development and therapy · 2019Article
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe emergence of multidrug resistant (MDR) pathogens is of great concern to the global health community. Our ability to effectively treat diseases is based on the discovery of potent drugs for the treatment of these challenging diseases. Traditional medicines are one of the major sources for the discovery of safe, effective and economical drug candidates. In order to validate its antibacterial, antifungal and insecticidal potentials with respect to traditional uses, we have screened for the first time Polygonum hydropiper against pathogenic bacterial, fungal strains and a variety of insects.
methodsPolygonum hydropiper samples including crude extract (Ph.Cr), subsequent fractions; n-hexane (Ph.Hex), chloroform (Ph.Chf), ethyl acetate (Ph.EtAc), n-Butanol (Ph.Bt), aqueous (Ph.Aq) and crude saponins (Ph.Sp) were tested against pathogenic bacterial and fungal strains. Insecticidal activities were performed against Tribolium castaneum and Rhyzopertha dominica and Monomorium pharaonis. Ph.Cr was analyzed by gas chromatography-mass spectrometry (GC-MS) for preliminary identification of chemical constituents.
resultsIn disc diffusion assay, Ph.Chf, Ph.Hex, Ph.EtAc and Ph.Sp exhibited highest activity against Enterococcus faecalis. MICs of Ph.Chf against Enterococcus faecalis, Klebsiella pneumoniae, Escherichia coli, P. mirabilis, Staphylococcus aureus, Salmonella typhi and Pseudomonas aeruginosa were 32.00, 13.33, 10.66, 5.33, 64.00, 8.66 and 10.66 μg/ml respectively. MFC's of Ph.Chf against Aspergillus fumigatus, Aspergillus flavus, Aspergillus niger and Fusarium oxysporum were 16.66, 23.33, 125.00 and 46.66 μg/ml respectively. Ph.EtAc, Ph.Sp, Ph.Chf and Ph.Bt were most active fractions against T. castaneum and R. dominica. Ph.Sp being most active against A. punctatum exhibited LC
conclusionsP. hydropiper samples exhibited broad spectrum of activity against bacterial and fungal strains. Our results support previously reported insecticidal properties of saponins and may provide scientific justification for the ethno-medicinal uses of the plant.
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