Evidence map›Paper›PMID 27919043›Full record

ReviewBioscience reports2014

Ductal carcinoma in situ of the breast: morphological and molecular features implicated in progression.

Dirce M Carraro, Eliana V Elias, Victor P Andrade

Open access · goldAbstract readReview
In one paragraph

Review in Bioscience reports, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 53 citations in OpenAlex.

  1. Trial
  2. Article
  3. Review
  4. Article
  5. T-type Ca2+ channels and their relationship with pre-neoplastic and neoplastic lesions in the human breast.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2023
    Article
  6. Article
  7. Insights into the transition of ductal carcinomaCancer biology & medicine · 2022
    Article
  8. Article
  9. Article
  10. Article
  11. Identification of aberrant gene expression during breast ductal carcinomaThe Journal of international medical research · 2020
    Article
  12. Review
  13. Review
  14. Review
  15. Article
  16. Article
  17. Thioredoxin-interacting protein is an independent risk stratifier for breast ductal carcinoma in situ.Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc · 2018
    Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Dirce M CarraroLaboratory of Genomics and Molecular Biology, International Center of Research, A.C. Camargo Cancer Center, São Paulo, SP 01509-900, Brazil dirce.carraro@cipe.accamargo.org.br.
Eliana V EliasLaboratory of Genomics and Molecular Biology, International Center of Research, A.C. Camargo Cancer Center, São Paulo, SP 01509-900, Brazil.
Victor P AndradeDepartment of Anatomical Pathology, A.C. Camargo Cancer Center, São Paulo, S.P. 01509-900, Brazil.
AC Camargo Hospital · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The spread of mammographic screening programmes around the world, including in developing countries, has substantially contributed to the diagnosis of small non-palpable lesions, which has increased the detection rate of DCIS (ductal carcinoma in situ). DCIS is heterogeneous in several ways, such as its clinical presentation, morphology and genomic profile. Excellent outcomes have been reported; however, many questions remain unanswered. For example, which patients groups are overtreated and could instead benefit from minimal intervention and which patient groups require a more traditional multidisciplinary approach. The development of a comprehensive integrated analysis that includes the radiological, morphological and genetic aspects of DCIS is necessary to answer these questions. This review focuses on discussing the significant findings about the morphological and molecular features of DCIS and its progression that have helped to uncover the biological and genetic heterogeneity of this disease. The knowledge gained in recent years might allow the development of tailored clinical management for women with DCIS in the future.

Indexed as

Breast NeoplasmsCarcinoma, Intraductal, NoninfiltratingFemaleHumansBreast cancercancer progressionDuctal carcinoma in situ (DCIS)epithelial cellsinvasive breast carcinoma (IBC)microenvironment

Identifiers

PMID27919043
PMCPMC3894794
OpenAlexW1982767940

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.