Evidence map›Paper›PMID 27918958›Full record

ReviewCurrent opinion in virology2017

Drivers of airborne human-to-human pathogen transmission.

Sander Herfst, Michael Böhringer, Basel Karo, Philip Lawrence, Nicola S Lewis, Michael J Mina, Charles J Russell, John Steel, Rik L de Swart, Christian Menge

Abstract readReview
In one paragraph

Review in Current opinion in virology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
55citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

55 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
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  5. Deliberating the scientific evidence base for influenza transmission to raw milk consumers.Risk analysis : an official publication of the Society for Risk Analysis · 2025
    Review
  6. Article
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  9. Analysis of the potentially pathogenic bacteria of lower respiratory tract infections in children per-, during and post-COVID-19: a retrospective study.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2025
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  20. A multicentre retrospective cohort study on COVID-19-related physical interventions and adult hospital admissions for ENT infections.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Sander HerfstDepartment of Viroscience, Postgraduate School of Molecular Medicine, Erasmus MC, Wytemaweg 80, 3015 CN Rotterdam, The Netherlands. Electronic address: s.herfst@erasmusmc.nl.
Michael BöhringerFriedrich-Loeffler-Institut, Institute of Bacterial Infections and Zoonoses, Naumburger Str. 96a, 07743 Jena, Germany.
Basel KaroRobert Koch Institut, Department for Infectious Disease Epidemiology, Seestr. 10, 13353 Berlin, Germany; PhD Programme "Epidemiology", Braunschweig-Hannover, Germany.
Philip LawrenceUniversité de Lyon, UMRS 449, Laboratoire de Biologie Générale, Université Catholique de Lyon - EPHE, Lyon 69288, France; Molecular Basis of Viral Pathogenicity, International Centre for Research in Infectiology (CIRI), INSERM U1111 - CNRS UMR5308, Université Lyon 1, Ecole Normale Supérieure de Lyon, Lyon 69007, France.
Nicola S LewisCentre for Pathogen Evolution, Department of Zoology, University of Cambridge, Downing Street, Cambridge, United Kingdom.
Michael J MinaDepartment of Ecology and Evolutionary Biology, Princeton University, Princeton, NJ 08544, USA.
Charles J RussellDepartment of Infectious Diseases, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.
John SteelDepartment of Microbiology and Immunology, Emory University School of Medicine, Atlanta, GA 30322, USA.
Rik L de SwartDepartment of Viroscience, Postgraduate School of Molecular Medicine, Erasmus MC, Wytemaweg 80, 3015 CN Rotterdam, The Netherlands.
Christian MengeFriedrich-Loeffler-Institut, Institute of Molecular Pathogenesis, Naumburger Str. 96a, 07743 Jena, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Airborne pathogens - either transmitted via aerosol or droplets - include a wide variety of highly infectious and dangerous microbes such as variola virus, measles virus, influenza A viruses, Mycobacterium tuberculosis, Streptococcus pneumoniae, and Bordetella pertussis. Emerging zoonotic pathogens, for example, MERS coronavirus, avian influenza viruses, Coxiella, and Francisella, would have pandemic potential were they to acquire efficient human-to-human transmissibility. Here, we synthesize insights from microbiological, medical, social, and economic sciences to provide known mechanisms of aerosolized transmissibility and identify knowledge gaps that limit emergency preparedness plans. In particular, we propose a framework of drivers facilitating human-to-human transmission with the airspace between individuals as an intermediate stage. The model is expected to enhance identification and risk assessment of novel pathogens.

Indexed as

AerosolsAir MicrobiologyDisease Transmission, InfectiousBacterial InfectionsHumansVirus DiseasesAerosols

Identifiers

PMID27918958
PMCPMC7102691

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.