Evidence map›Paper›PMID 27918487›Full record

ReviewSensors (Basel, Switzerland)2016

Integrating Deoxyribozymes into Colorimetric Sensing Platforms.

Dingran Chang, Sandy Zakaria, Mimi Deng, Nicholas Allen, Kha Tram, Yingfu Li

Abstract readReview
In one paragraph

Review in Sensors (Basel, Switzerland), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Recent Advances in Aptamer Sensors.Sensors (Basel, Switzerland) · 2021
    Review
  8. Review
  9. Article
  10. Review
  11. Review
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Dingran ChangDepartment of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, ON L8S 4K1, Canada. changd3@mcmaster.ca.
Sandy ZakariaDepartment of Biomedical Engineering, McMaster University, Hamilton, ON L8S 4K1, Canada. zakarias@mcmaster.ca.
Mimi DengDepartment of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, ON L8S 4K1, Canada. dengxx3@mcmaster.ca.
Nicholas AllenDepartment of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, ON L8S 4K1, Canada. allenn5@mcmaster.ca.
Kha TramDepartment of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, ON L8S 4K1, Canada. tramkq@mcmaster.ca.
Yingfu LiDepartment of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, ON L8S 4K1, Canada. liying@mcmaster.ca.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Biosensors are analytical devices that have found a variety of applications in medical diagnostics, food quality control, environmental monitoring and biodefense. In recent years, functional nucleic acids, such as aptamers and nucleic acid enzymes, have shown great potential in biosensor development due to their excellent ability in target recognition and catalysis. Deoxyribozymes (or DNAzymes) are single-stranded DNA molecules with catalytic activity and can be isolated to recognize a wide range of analytes through the process of in vitro selection. By using various signal transduction mechanisms, DNAzymes can be engineered into fluorescent, colorimetric, electrochemical and chemiluminescent biosensors. Among them, colorimetric sensors represent an attractive option as the signal can be easily detected by the naked eye. This reduces reliance on complex and expensive equipment. In this review, we will discuss the recent progress in the development of colorimetric biosensors that make use of DNAzymes and the prospect of employing these sensors in a range of chemical and biological applications.

Indexed as

Biosensing TechniquesColorimetryColoring AgentsDNA, CatalyticGoldMetal NanoparticlesColoring AgentsDNA, CatalyticGoldbiosensorscolorimetric sensorsDNAzymes

Identifiers

PMID27918487
PMCPMC5191042

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.