ReviewMolecules (Basel, Switzerland)2016
Phenols and Polyphenols as Carbonic Anhydrase Inhibitors.
Review in Molecules (Basel, Switzerland), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
32 citing papers in PubMed, 104 citations in OpenAlex.
- Comprehensive Evaluation of Peonidin: Antioxidant and Multi-Enzyme Inhibitory Abilities with Molecular Docking Insights.Molecules (Basel, Switzerland) · 2026Article
- LC-MS/MS characterization, biological activity, and carbonic anhydrase inhibitory potential of five medicinal plant extracts from Romania and Türkiye.Scientific reports · 2026Article
- Assessment of Different Strategies for Composting of the Two-Phase Olive Mill Solid Waste: A Demonstrative Scale.ACS agricultural science & technology · 2025Article
- Structure-function relationships in solvatochromic fluorophores targeting human and bovine carbonic anhydrases.Journal of inorganic biochemistry · 2025Article
- Screening of ligands for carbonic anhydrase II from traditional Chinese medicine Kansui by combination of in silico target prediction, surface plasmon resonance, and UPLC-HR-MS/MS.Analytical and bioanalytical chemistry · 2025Article
- Discover the Power of Lithospermic Acid as Human Carbonic Anhydrase VA and Pancreatic Lipase Inhibitor Through In Silico and In Vitro Studies.Archiv der Pharmazie · 2025Article
- Unprecedented carbonic anhydrase inhibition mechanism: Targeting histidine 64 side chain through a halogen bond.Archiv der Pharmazie · 2025Article
- Article
- Visible-light TiOChemical science · 2024Article
- Phenols and GABAFrontiers in pharmacology · 2024Review
- Development of novel anilinoquinazoline-based carboxylic acids as non-classical carbonic anhydrase IX and XII inhibitors.Journal of enzyme inhibition and medicinal chemistry · 2023Article
- Identification of anti-cyanobacterial leads targeting carbonic anhydrase from phytochemical database usingBiotechnologia · 2023Article
- Functional genomic effects of indels using Bayesian genome-phenome wide association studies in sorghum.Frontiers in genetics · 2023Article
- Inhibition studies of the protozoan α-carbonic anhydrase fromJournal of enzyme inhibition and medicinal chemistry · 2022Article
- Controlled Atmosphere Improves the Quality, Antioxidant Activity and Phenolic Content of Yellow Peach during the Shelf Life.Antioxidants (Basel, Switzerland) · 2022Article
- Seleno Containing Compounds as Potent and Selective Antifungal Agents.ACS infectious diseases · 2022Article
- Article
- Thiosemicarbazide-Substituted Coumarins as Selective Inhibitors of the Tumor Associated Human Carbonic Anhydrases IX and XII.Molecules (Basel, Switzerland) · 2022Article
- Enzymes Inhibition and Antioxidant Potential of Medicinal Plants Growing in Oman.BioMed research international · 2022Article
- Reconsidering anion inhibitors in the general context of drug design studies of modulators of activity of the classical enzyme carbonic anhydrase.Journal of enzyme inhibition and medicinal chemistry · 2021Review
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Phenols are among the largest and most widely distributed groups of secondary metabolites within the plant kingdom. They are implicated in multiple and essential physiological functions. In humans they play an important role as microconstituents of the daily diet, their consumption being considered healthy. The physical and chemical properties of phenolic compounds make these molecules versatile ligands, capable of interacting with a wide range of targets, such as the Carbonic Anhydrases (CAs, EC 4.2.1.1). CAs reversibly catalyze the fundamental reaction of CO₂ hydration to bicarbonate and protons in all living organisms, being actively involved in the regulation of a plethora of patho/physiological processes. This review will discuss the most recent advances in the search of naturally occurring phenols and their synthetic derivatives that inhibit the CAs and their mechanisms of action at molecular level. Plant extracts or mixtures are not considered in the present review.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.