Evidence map›Paper›PMID 27918339›Full record

ArticleFemale pelvic medicine & reconstructive surgery

Irritable Bowel Syndrome and Quality of Life in Women With Fecal Incontinence.

Alayne D Markland, J Eric Jelovsek, David D Rahn, Lu Wang, Leah Merrin, Ashok Tuteja, Holly E Richter, Susan Meikle, Pelvic Floor Disorders Network

Abstract readMulticenter Study
In one paragraph

Article in Female pelvic medicine & reconstructive surgery. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 7 institutions in 1 country.

Alayne D MarklandFrom the *Birmingham Veterans Affairs Medical Center, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL; †Obstetrics, Gynecology, and Women's Health, Cleveland Clinic, Cleveland, OH; ‡Obstetrics and Gynecology, University of Texas Southwestern Medical Center, Dallas, TX; §Biostatistics, University of Michigan, Ann Arbor, MI, United States; ∥Obstetrics and Gynecology, University of California, San Diego, San Diego, CA; ¶Medicine, Salt Lake City Veterans Affairs Medical Center, University of Utah, Salt Lake City, UT; **Obstetrics and Gynecology, University of Alabama at Birmingham, Birmingham, AL; and ††Eunice Kennedy Shriver NICHD, National Institutes of Health, Bethesda, MD.
J Eric Jelovsek
David D Rahn
Lu Wang
Leah Merrin
Ashok Tuteja
Holly E Richter
Susan Meikle
Pelvic Floor Disorders Network
Birmingham VA Medical Center · USCleveland Clinic · USEunice Kennedy Shriver National Institute of Child Health and Human Development · USThe University of Texas Southwestern Medical Center · USUniversity of California, San Diego · USUniversity of Michigan–Ann Arbor · USUniversity of Utah · US

Funding

Pelvic Floor Disorders Network Data Coordinating Center (U01)U01HD069031 · NICHD · RESEARCH TRIANGLE INSTITUTE · PI GANTZ, MARIE G · 2011 to 2015
$19.7M
Perioperative Pelvic Floor Rehab: A Rrandomized TrialU10HD041261 · NICHD · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI RICHTER, HOLLY E · 2001 to 2015
$5.1M
UNC Pelvic Floor Disorders Research CollaborativeU10HD041267 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI VISCO, ANTHONY G · 2001 to 2015
$5.0M
UAB Continence Treatment Center U01DK060380 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI RICHTER, HOLLY E · 2001 to 2009
$3.9M
Pelvic Floor Disorders NetworkU10HD054214 · NICHD · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI LUKACZ, EMILY S. · 2006 to 2015
$3.3M
The Cleveland Clinic Clinical SiteU10HD054215 · NICHD · CLEVELAND CLINIC LERNER COM-CWRU · PI BARBER, MATTHEW D · 2006 to 2015
$3.2M
Brown/WIH Pelvic Floor Disorders Network Site (UG1)UG1HD069013 · NICHD · WOMEN AND INFANTS HOSPITAL-RHODE ISLAND · PI Vivian W Sung · 2016 to 2026
$3.1M
Pelvic Floor Disorders Network 2021UG1HD054241 · NICHD · UT SOUTHWESTERN MEDICAL CENTER · PI David Dwight Rahn · 2016 to 2026
$3.0M
Pelvic Floor Disorders Network Clinical Sites (U10)U10HD069010 · NICHD · UNIVERSITY OF PENNSYLVANIA · PI ARYA, LILY A · 2011 to 2015
$1.7M
Brown/WIH Pelvic Floor Disorders Network SiteU10HD069013 · NICHD · WOMEN AND INFANTS HOSPITAL-RHODE ISLAND · PI SUNG, VIVIAN W · 2011 to 2015
$1.6M
Pittsburgh Pelvic Floor Research ProgramU10HD069006 · NICHD · MAGEE-WOMEN'S RES INST AND FOUNDATION · PI ZYCZYNSKI, HALINA M · 2011 to 2015
$1.6M
RCT of Hypnotherapy vs Tpolterodine for OAB: Voiding and Brain Activation ChangesU10HD069025 · NICHD · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI ROGERS, REBECCA GLENN · 2011 to 2015
$1.6M
NICHD NIH HHS U01 HD069031NICHD NIH HHS U10 HD041261NICHD NIH HHS U10 HD041267NICHD NIH HHS U10 HD054214NICHD NIH HHS U10 HD054215NICHD NIH HHS U10 HD069006NICHD NIH HHS U10 HD069010NICHD NIH HHS U10 HD069013NICHD NIH HHS U10 HD069025NICHD NIH HHS UG1 HD041261NICHD NIH HHS UG1 HD054241NICHD NIH HHS UG1 HD069006NICHD NIH HHS UG1 HD069013NIDDK NIH HHS U01 DK060380
6 · The paper itself

Abstract

objectivesThe objectives of this work were to determine the prevalence of irritable bowel syndrome (IBS) and IBS subtypes in women presenting for fecal incontinence (FI) treatment and to assess the impact of IBS on FI symptoms and quality of life (QOL).

methodsIn this multicenter prospective cohort study, women reported at least monthly solid, liquid, or mucus FI. Rome III clinical criteria defined IBS. Women also self-reported having an IBS diagnosis. Baseline questionnaires included the following: Modified Manchester Health Questionnaire, Fecal Incontinence Severity Index, Bristol Stool Scale, Pelvic Floor Distress Inventory, and the Pelvic Floor Impact Questionnaire.

resultsOf the 133 women enrolled, 119 completed Rome III IBS questionnaires, and 111 reported on whether they had a previous diagnosis of IBS. The prevalence of IBS was 31% (95% confidence interval [CI], 22.9%-40.2%) according to the Rome III IBS criteria. The most common subtypes were IBS-mixed (41%) and IBS-diarrhea (35%). Twenty-four (22%) of 111 patients had a previous diagnosis of IBS. Among women who met Rome III IBS criteria, 23 (66%) of 35 women had never had a diagnosis of IBS. Women with FI and IBS reported significantly worse QOL compared to women without IBS despite similar FI severity and stool consistency.

conclusionsIrritable bowel syndrome negatively affects QOL and affects one third of women with FI presenting for care in tertiary centers. Our findings suggest that assessment of IBS symptoms and diagnosis may be important for women presenting for FI treatment.

Indexed as

Quality of LifeAgedFecal IncontinenceFemaleHumansIrritable Bowel SyndromeMiddle AgedPrevalenceProspective StudiesSelf ReportSeverity of Illness Index

Identifiers

PMID27918339
PMCPMC5404998
OpenAlexW2557235621

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.