Evidence map›Paper›PMID 27917957›Full record

ArticleScientific reports2016

Refined purification strategy for reliable proteomic profiling of HDL

Michael Holzer, Sabine Kern, Ruth Birner-Grünberger, Sanja Curcic, Akos Heinemann, Gunther Marsche

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 34 citations in OpenAlex.

  1. The HDL lipidome is widely remodeled by fast food versus Mediterranean diet in 4 days.Metabolomics : Official journal of the Metabolomic Society · 2019
    Trial
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  13. Endothelial lipase increases antioxidative capacity of high-density lipoprotein.Biochimica et biophysica acta. Molecular and cell biology of lipids · 2019
    Article
  14. Deepening our understanding of HDL proteome.Expert review of proteomics · 2019
    Review
  15. Article
  16. Article
  17. Article
  18. Review
  19. Secretory phospholipase AScientific reports · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Michael HolzerInstitute of Experimental and Clinical Pharmacology, Medical University of Graz, Austria.
Sabine KernInstitute of Experimental and Clinical Pharmacology, Medical University of Graz, Austria.
Ruth Birner-GrünbergerInstitute of Pathology and Proteomics Core Facility, Center for Medical Research, Medical University of Graz, Austria.
Sanja CurcicInstitute of Experimental and Clinical Pharmacology, Medical University of Graz, Austria.
Akos HeinemannInstitute of Experimental and Clinical Pharmacology, Medical University of Graz, Austria.
Gunther MarscheInstitute of Experimental and Clinical Pharmacology, Medical University of Graz, Austria.
Medical University of Graz · AT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Proteomics have extended the list of high-density lipoprotein (HDL) associated proteins to about 90. One of the major issues of global protein characterization is establishing specificity of association as opposed to contamination, a fact which has never been addressed for isolated HDL. We have developed a refined purification strategy to isolate HDL by density, followed by purification by size to generate "highly purified" fractions of HDL

Indexed as

Cross-Linking ReagentsFatty AcidsHumansImmunoblottingLipoproteins, HDLPhospholipases A2PhospholipidsProteomeProteomicsCross-Linking ReagentsFatty AcidsLipoproteins, HDLPhospholipases A2PhospholipidsProteome

Identifiers

PMID27917957
PMCPMC5137140
OpenAlexW2560694811

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.