Evidence map›Paper›PMID 27917928›Full record

ArticleScientific reports2016

Renal Denervation Improves the Baroreflex and GABA System in Chronic Kidney Disease-induced Hypertension.

Hsin-Hung Chen, Pei-Wen Cheng, Wen-Yu Ho, Pei-Jung Lu, Chi-Cheng Lai, Yang-Ming Tseng, Hua-Chang Fang, Gwo-Ching Sun, Michael Hsiao, Chun-Peng Liu and 1 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
2.9field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Review
  5. Article
  6. The role of afferent renal nerves in regulating sympathetic outflow via central nervous system mechanisms.Hypertension research : official journal of the Japanese Society of Hypertension · 2024
    Article
  7. Article
  8. Article
  9. Review
  10. Review
  11. Review
  12. Article
  13. Drug vector representation: a tool for drug similarity analysis.Molecular genetics and genomics : MGG · 2020
    Article
  14. Article
  15. Article
  16. Differences in Serum Amino Acid Phenotypes Among Patients with Diabetic Nephropathy, Hypertensive Nephropathy, and Chronic Nephritis.Medical science monitor : international medical journal of experimental and clinical research · 2019
    Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 1 country.

Hsin-Hung ChenDepartment of Medical Education and Research, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan.
Pei-Wen ChengDepartment of Medical Education and Research, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan.
Wen-Yu HoDivision of General Internal Medicine, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan.
Pei-Jung LuGraduate Institute of Clinical Medicine, National Cheng-Kung University, Tainan, Taiwan.
Chi-Cheng LaiCardiovascular Center, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan.
Yang-Ming TsengDepartment of Pathology and Laboratory Medicine, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan.
Hua-Chang FangDivision of Nephrology, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan.
Gwo-Ching SunDepartment of Anesthesiology, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan.
Michael HsiaoGenomics Research Center, Academia Sinica, Taipei, Taiwan.
Chun-Peng LiuDepartment of Administration, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan.
Ching-Jiunn TsengDepartment of Medical Education and Research, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan.
Kaohsiung Veterans General Hospital · TWGenomics Research Center, Academia Sinica · TWKaohsiung Medical University · TWKaohsiung Medical University Chung-Ho Memorial Hospital · TWNational Cheng Kung University · TWNational Yang Ming Chiao Tung University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hypertensive rats with chronic kidney disease (CKD) exhibit enhanced gamma-aminobutyric acid (GABA)

Indexed as

AnimalsBaroreflexBlood PressureDenervationHumansHypertensionHypertension, RenalKidneyNephrectomyNephritisNeurons, AfferentPhenolRatsReceptors, GABA-BRenal Insufficiency, ChronicSolitary NucleusPhenolReceptors, GABA-B

Identifiers

PMID27917928
PMCPMC5137107
OpenAlexW2560169719

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.