Evidence map›Paper›PMID 27917460›Full record

Trial reportJournal of abnormal child psychology2017

Moderators of Parent Training for Disruptive Behaviors in Young Children with Autism Spectrum Disorder.

Luc Lecavalier, Tristram Smith, Cynthia Johnson, Karen Bearss, Naomi Swiezy, Michael G Aman, Denis G Sukhodolsky, Yanhong Deng, James Dziura, Lawrence Scahill

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of abnormal child psychology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Trial
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  11. Parent Education for Young Children With Autism and Disruptive Behavior: Response to Active Control Treatment.Journal of clinical child and adolescent psychology : the official journal for the Society of Clinical Child and Adolescent Psychology, American Psychological Association, Division 53 · 2018
    Trial
  12. Article
  13. Article
  14. Article
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  16. Iterative redesign of a caregiver-mediated intervention for use in educational settings.Autism : the international journal of research and practice · 2022
    Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Luc LecavalierNisonger Center and Department of Psychology, Ohio State University, 371D McCampbell Hall, 1581 Dodd Dr., Columbus, OH, 43210, USA. Luc.Lecavalier@osumc.edu.ORCID http://orcid.org/0000-0002-1162-659X
Tristram SmithUniversity of Rochester Medical Center School of Medicine and Dentistry, 601 Elmwood Ave, Box 671, Rochester, NY, 14642, USA.
Cynthia JohnsonDepartment of Clinical and Health Psychology, 1225 Center Dr., Room 3130, PO Box 100165, Gainesville, FL, 32610-0165, USA.
Karen BearssDepartment of Psychiatry and Behavioral Sciences, 4909 25th Ave NE, Seattle, WA, 98105, USA.
Naomi SwiezyIndiana University Riley Hospital for Children, 705 Riley Hospital Drive, Indianapolis, IN, 46202, USA.
Michael G AmanOhio State University, 1581 Dodd Dr., Columbus, OH, 43210, USA.
Denis G SukhodolskyYale Child Study Center, 230 South Frontage Road, PO Box 207900, New Haven, CT, 06520-7900, USA.
Yanhong DengYale Center for Analytical Sciences, 300 George Street Suite 555, New Haven, CT, 06511, USA.
James DziuraYale Center for Analytical Sciences, 300 George Street Suite 555, New Haven, CT, 06511, USA.
Lawrence ScahillMarcus Autism Center, 1920 Briarcliff Road, Atlanta, GA, 30329-4010, USA.

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Yale Pathology Tissue Services Shared ResourceP30CA016359 · NCI · YALE UNIVERSITY · PI DAVID L RIMM · 1985 to 2026
$85.0M
YALE UNIVERSITY CLINICAL AND TRANSLATIONAL SCIENCE AWARD PROGRAMUL1RR024139 · NCRR · YALE UNIVERSITY · PI SHERWIN, ROBERT S · 2006 to 2011
$56.8M
Atlanta Clinical and Translational Science Institute (ACTSI) RenewalUL1TR000454 · NCATS · EMORY UNIVERSITY · PI STEPHENS, DAVID S · 2012 to 2016
$25.8M
The University of Rochester's Clinical and Translational Science InstituteUL1TR000042 · NCATS · UNIVERSITY OF ROCHESTER · PI BENNETT, NANCY M, KIEBURTZ, KARL D. · 2012 to 2015
$14.4M
1/5-Randomized Trial of Parent Training for Young Children with AutismR01MH081148 · NIMH · YALE UNIVERSITY · PI SCAHILL, LAWRENCE D. · 2010 to 2014
$1.8M
3/5-Randomized Trial of Parent Training for Young Children with AutismR01MH080906 · NIMH · UNIVERSITY OF ROCHESTER · PI SMITH, TRISTRAM H · 2010 to 2014
$1.2M
5/5-Randomized Trial of Parent Training for Young Children with AutismR01MH080965 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI JOHNSON, CYNTHIA R · 2010 to 2014
$1.2M
4/5-Randomized Trial of Parent Training for Young Children with AutismR01MH081221 · NIMH · INDIANA UNIVERSITY INDIANAPOLIS · PI SWIEZY, NAOMI BETH · 2010 to 2014
$1.2M
2/5-Randomized Trial of Parent Training for Young Children with AutismR01MH081105 · NIMH · OHIO STATE UNIVERSITY · PI LECAVALIER, LUC · 2010 to 2014
$1.1M
Neurobiology of Behavior Therapy for Children with Tourette SyndromeK01MH079130 · NIMH · YALE UNIVERSITY · PI SUKHODOLSKY, DENIS G · 2008 to 2012
$833k
NCATS NIH HHS UL1 TR000042NCATS NIH HHS UL1 TR000454NCATS NIH HHS UL1 TR001863NCI NIH HHS P30 CA016359NCRR NIH HHS UL1 RR024139NIMH NIH HHS K01 MH079130NIMH NIH HHS R01 MH080906NIMH NIH HHS R01 MH080965NIMH NIH HHS R01 MH081105NIMH NIH HHS R01 MH081148NIMH NIH HHS R01 MH081221
6 · The paper itself

Abstract

We conducted a 6 month, randomized trial of parent training (PT) versus a parent education program (PEP) in 180 young children (158 boys, 22 girls), ages 3-7 years, with autism spectrum disorder (ASD). PT was superior to PEP in decreasing disruptive and noncompliant behaviors. In the current study, we assess moderators of treatment response in this trial. Thirteen clinical and demographic variables were evaluated as potential moderators of three outcome variables: the Aberrant Behavior Checklist-Irritability subscale (ABC-I), Home Situations Questionnaire (HSQ), and Clinical Global Impressions-Improvement Scale (CGI-I). We used an intent-to-treat model and random effects regression. Neither IQ nor ASD severity moderated outcome on the selected outcome measures. Severity of Attention Deficit Hyperactivity Disorder (ADHD) and anxiety moderated outcomes on the ABC-I and HSQ. For instance, there was a 6.6 point difference on the ABC-I between high and low ADHD groups (p = .05) and a 5.3 point difference between high and low Anxiety groups (p = .04). Oppositional defiant disorder symptoms and household income moderated outcomes on the HSQ. None of the baseline variables moderated outcome on the CGI-I. That IQ and ASD symptom severity did not moderate outcome suggests that PT is likely to benefit a wide range of children with ASD and disruptive behavior.

Indexed as

Child BehaviorProblem BehaviorAnxietyAttention Deficit Disorder with HyperactivityAutism Spectrum DisorderChildChild, PreschoolComorbidityEducation, NonprofessionalFamily TherapyFemaleHumansMaleADHDAnxietyAutism spectrum disorderModeratorParent training

Identifiers

PMID27917460
PMCPMC5459681

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.