Evidence map›Paper›PMID 27917379›Full record

ReviewFrontiers in chemistry2016

Current Understanding of the Correlation of Lignin Structure with Biomass Recalcitrance.

Mi Li, Yunqiao Pu, Arthur J Ragauskas

Abstract readReview
In one paragraph

Review in Frontiers in chemistry, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 96 papers.

0numbers the graph read from it
0cells of the map it votes in
96citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

96 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
  5. The Formation of Covalent Linkages in Lignocellulosic Biomass via the Oxocarbenium Intermediate.Chemphyschem : a European journal of chemical physics and physical chemistry · 2026
    Article
  6. Article
  7. Origins of Noncovalent Interactions in Lignocellulosic Biomass and Potential Implications on Recalcitrance.Chemphyschem : a European journal of chemical physics and physical chemistry · 2026
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Photosensitizer-conjugated lignin nanoparticles for photodynamic antimicrobial inactivation.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2025
    Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article

36 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Mi LiBioEnergy Science Center, Biosciences Division, Joint Institute of Biological Science, Oak Ridge National Laboratory Oak Ridge, TN, USA.
Yunqiao PuBioEnergy Science Center, Biosciences Division, Joint Institute of Biological Science, Oak Ridge National Laboratory Oak Ridge, TN, USA.
Arthur J RagauskasBioEnergy Science Center, Biosciences Division, Joint Institute of Biological Science, Oak Ridge National LaboratoryOak Ridge, TN, USA; Department of Chemical and Bimolecular Engineering, University of Tennessee KnoxvilleKnoxville, TN, USA; Department of Forestry, Wildlife, and Fisheries, Center for Renewable Carbon, University Tennessee Institute of AgricultureKnoxville, TN, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lignin, a complex aromatic polymer in terrestrial plants, contributes significantly to biomass recalcitrance to microbial and/or enzymatic deconstruction. To reduce biomass recalcitrance, substantial endeavors have been exerted on pretreatment and lignin engineering in the past few decades. Lignin removal and/or alteration of lignin structure have been shown to result in reduced biomass recalcitrance with improved cell wall digestibility. While high lignin content is usually a barrier to a cost-efficient application of bioresources to biofuels, the direct correlation of lignin structure and its concomitant properties with biomass remains unclear due to the complexity of cell wall and lignin structure. Advancement in application of biorefinery to production of biofuels, chemicals, and bio-derived materials necessitates a fundamental understanding of the relationship of lignin structure and biomass recalcitrance. In this mini-review, we focus on recent investigations on the influence of lignin chemical properties on bioprocessability-pretreatment and enzymatic hydrolysis of biomass. Specifically, lignin-enzyme interactions and the effects of lignin compositional units, hydroxycinnamates, and lignin functional groups on biomass recalcitrance have been highlighted, which will be useful not only in addressing biomass recalcitrance but also in deploying renewable lignocelluloses efficiently.

Indexed as

biomass recalcitrancecell wallenzymatic hydrolysislignin structurepretreatment

Identifiers

PMID27917379
PMCPMC5114238

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.