ArticleSpringerPlus2016
Cholecystectomy and duodenogastric reflux: interacting effects over the gastric mucosa.
Article in SpringerPlus, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- Association Between Cholecystectomy and Gastroesophageal Inflammatory Findings After Sleeve Gastrectomy: Endoscopic and Metabolic Evaluation.Obesity surgery · 2026Observational
- The Impact of Cholecystectomy on Bile Reflux After One Anastomosis Gastric Bypass.Obesity surgery · 2025Observational
- Associations between sleeve gastrectomy, cholecystectomy, and gastroesophageal reflux disease in obese patients: an integrative review.Revista do Colegio Brasileiro de Cirurgioes · 2025Review
- Assessment of the risk factors of duodenogastric reflux in relation to different dietary habits in a Chinese population of the Zhangjiakou area.Food & nutrition research · 2023Article
- Bile reflux alters the profile of the gastric mucosa microbiota.Frontiers in cellular and infection microbiology · 2022Article
- Development of a novel model of cholecystectomy in subsequently ovariectomized mice and characterization of metabolic and gastrointestinal phenotypes: a pilot study.BMC gastroenterology · 2021Article
- Biliary hyperkinesia in adolescents-it isn't all hype!Translational gastroenterology and hepatology · 2021Article
- The Effect of Primary Duodenogastric Bile Reflux on the Presence and Density ofMedicina (Kaunas, Lithuania) · 2019Article
- Article
- Does perioperative intravenous dextrose reduce postoperative nausea and vomiting? A systematic review and meta-analysis.Therapeutics and clinical risk management · 2018Article
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimsTo evaluate association between duodenogastric reflux and early gastric mucosal changes before and after the cholecystectomy procedure. MATERIALS AND
methodsPatients were evaluated with preoperative and postoperative endoscopy and endoscopic biopsy. Demographic and clinical characteristics, histological parameters, presence of duodenogastric reflux, and Updated Sydney scores were noted.
resultsA total of fifty patients who obeyed the follow-up were enrolled into the study. Median age of the patients was 43 years (range 25-84). Male-female ratio was 0.51 (17/33). Duodenogastric reflux % and Updated Sydney scores before and after cholecystectomy were 24 (48%) versus 39 (78%) and 2.38 ± 2.21 versus 3.46 ± 3.05, respectively (p = 0.001, p < 0.000). Mucosal inflammation degree showed significant increase in 15 (30%) patients, decrease in 7 (14%) patients and equality in 28 (56%) patients (p = 0.037). Neutrophil activation degree was significantly higher in 21 (42%) patients, lower in 5 (10%) patients after the surgery (p = 0.005). Postoperative glandular atrophy degree was also higher in 13 (26%) patients and equal in 37 (74%) patients (p = 0.001). Pre- and postoperative degree of intestinal metaplasia and
conclusionCholecystectomy is a potent inducer of pathologic duodenogastric reflux. Early onset of duodenogastric reflux and underlying
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