ArticleBiomicrofluidics2016
In-plane microvortices micromixer-based AC electrothermal for testing drug induced death of tumor cells.
Article in Biomicrofluidics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed.
- Synchronous oscillatory electro-inertial focusing of microparticles.Biomicrofluidics · 2023Article
- Manipulation of Elastic Instability of Viscoelastic Fluid in a Rhombus Cross Microchannel.Polymers · 2022Article
- Numerical and Experimental Study of Cross-Sectional Effects on the Mixing Performance of the Spiral Microfluidics.Micromachines · 2021Article
- AC Electrothermal Effect in Microfluidics: A Review.Micromachines · 2019Review
- Multiparameter toxicity screening on a chip: Effects of UV radiation and titanium dioxide nanoparticles on HaCaT cells.Biomicrofluidics · 2019Article
- Comparison of Micro-Mixing in Time Pulsed Newtonian Fluid and Viscoelastic Fluid.Micromachines · 2019Article
- Simultaneous Pumping and Mixing of Biological Fluids in a Double-Array Electrothermal Microfluidic Device.Micromachines · 2019Article
- Joule heating-induced particle manipulation on a microfluidic chip.Biomicrofluidics · 2019Article
- 3D printed selectable dilution mixer pumps.Biomicrofluidics · 2019Article
- A Review on Micromixers.Micromachines · 2017Review
- Electrokinetic instability in microchannel ferrofluid/water co-flows.Scientific reports · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Herein, we first describe a perfusion chip integrated with an AC electrothermal (ACET) micromixer to supply a uniform drug concentration to tumor cells. The in-plane fluid microvortices for mixing were generated by six pairs of reconstructed novel ACET asymmetric electrodes. To enhance the mixing efficiency, the novel ACET electrodes with rotating angles of 0°, 30°, and 60° were investigated. The asymmetric electrodes with a rotating angle of 60° exhibited the highest mixing efficiency by both simulated and experimental results. The length of the mixing area is 7 mm, and the mixing efficiency is 89.12% (approximate complete mixing) at a voltage of 3 V and a frequency of 500 kHz. The applicability of our micromixer with electrodes rotating at 60° was demonstrated by the drug (tamoxifen) test of human breast cancer cells (MCF-7) for five days, which implies that our ACET in-plane microvortices micromixer has great potential for the application of drug induced rapid death of tumor cells and mixing of biomaterials in organs-on-a-chip systems.
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.