Evidence map›Paper›PMID 27917162›Full record

ArticleFrontiers in microbiology2016

Activity of Scorpion Venom-Derived Antifungal Peptides against Planktonic Cells of

Fernanda Guilhelmelli, Nathália Vilela, Karina S Smidt, Marco A de Oliveira, Alice da Cunha Morales Álvares, Maria C L Rigonatto, Pedro H da Silva Costa, Aldo H Tavares, Sônia M de Freitas, André M Nicola and 7 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in microbiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed
3.1field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 63 citations in OpenAlex.

  1. Scorpion Peptides in Antiviral Drug Discovery: An In-depth Review.Probiotics and antimicrobial proteins · 2026
    Review
  2. Article
  3. Review
  4. Review
  5. Review
  6. Review
  7. Review
  8. Characterization ofFrontiers in pharmacology · 2025
    Article
  9. Review
  10. Review
  11. Review
  12. Synergic Effect of the Antimicrobial Peptide ToAP2 and Fluconazole onInternational journal of molecular sciences · 2024
    Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 2 institutions in 1 country.

Fernanda GuilhelmelliLaboratory of Molecular Biology, Department of Cellular Biology, Institute of Biological Sciences, University of Brasília Brasília, Brazil.
Nathália VilelaLaboratory of Molecular Biology, Department of Cellular Biology, Institute of Biological Sciences, University of Brasília Brasília, Brazil.
Karina S SmidtLaboratory of Applied Immunology, Department of Cellular Biology, Institute of Biological Sciences, University of Brasília Brasília, Brazil.
Marco A de OliveiraLaboratory of Molecular Biology, Department of Cellular Biology, Institute of Biological Sciences, University of Brasília Brasília, Brazil.
Alice da Cunha Morales ÁlvaresLaboratory of Molecular Biophysics, Department of Cellular Biology, Institute of Biological Sciences, University of Brasília Brasília, Brazil.
Maria C L RigonattoLaboratory of Applied Immunology, Department of Cellular Biology, Institute of Biological Sciences, University of Brasília Brasília, Brazil.
Pedro H da Silva CostaLaboratory of Applied Immunology, Department of Cellular Biology, Institute of Biological Sciences, University of Brasília Brasília, Brazil.
Aldo H TavaresLaboratory of Applied Immunology, Department of Cellular Biology, Institute of Biological Sciences, University of Brasília Brasília, Brazil.
Sônia M de FreitasLaboratory of Molecular Biophysics, Department of Cellular Biology, Institute of Biological Sciences, University of Brasília Brasília, Brazil.
André M NicolaFaculty of Medicine, University of Brasília Brasília, Brazil.
Octávio L FrancoCenter of Proteomic and Biochemistry Analysis, Post Graduation in Biotechnology and Genomic Sciences, Catholic University of Brasília Brasília, Brazil.
Lorena da Silveira DerengowskiLaboratory of Molecular Biology, Department of Cellular Biology, Institute of Biological Sciences, University of Brasília Brasília, Brazil.
Elisabeth F SchwartzLaboratory of Neuropharmacology, Department of Physiological Sciences, Institute of Biological Sciences, University of Brasília Brasília, Brazil.
Márcia R MortariLaboratory of Neuropharmacology, Department of Physiological Sciences, Institute of Biological Sciences, University of Brasília Brasília, Brazil.
Anamélia L BoccaLaboratory of Applied Immunology, Department of Cellular Biology, Institute of Biological Sciences, University of Brasília Brasília, Brazil.
Patrícia AlbuquerqueLaboratory of Molecular Biology, Department of Cellular Biology, Institute of Biological Sciences, University of BrasíliaBrasília, Brazil; Faculty of Ceilândia, University of BrasíliaBrasília, Brazil.
Ildinete Silva-PereiraLaboratory of Molecular Biology, Department of Cellular Biology, Institute of Biological Sciences, University of Brasília Brasília, Brazil.
Universidade de Brasília · BRUniversidade Católica de Brasília · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The incidence of fungal infections has been increasing in the last decades, while the number of available antifungal classes remains the same. The natural and acquired resistance of some fungal species to available therapies, associated with the high toxicity of these drugs on the present scenario and makes an imperative of the search for new, more efficient and less toxic therapeutic choices. Antimicrobial peptides (AMPs) are a potential class of antimicrobial drugs consisting of evolutionarily conserved multifunctional molecules with both microbicidal and immunomodulatory properties being part of the innate immune response of diverse organisms. In this study, we evaluated 11 scorpion-venom derived non-disulfide-bridged peptides against

Indexed as

antifungal drugsantimicrobial peptidesCandida albicansCandida spp.Cryptococcus neoformansscorpions venom

Identifiers

PMID27917162
PMCPMC5114273
OpenAlexW2551912621

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.