Evidence map›Paper›PMID 27917108›Full record

ArticleFrontiers in molecular neuroscience2016

Structural and Functional Consequences of Connexin 36 (Cx36) Interaction with Calmodulin.

Ryan C F Siu, Ekaterina Smirnova, Cherie A Brown, Christiane Zoidl, David C Spray, Logan W Donaldson, Georg Zoidl

Open access · goldAbstract read
In one paragraph

Article in Frontiers in molecular neuroscience, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
1.0field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 28 citations in OpenAlex.

  1. Defining the electrical synapse.Nature reviews. Neuroscience · 2026
    Review
  2. Article
  3. Review
  4. Review
  5. Article
  6. Review
  7. Review
  8. Article
  9. CaInternational journal of molecular sciences · 2023
    Article
  10. Article
  11. Review
  12. Article
  13. The Roles of Calmodulin and CaMKII in Cx36 Plasticity.International journal of molecular sciences · 2021
    Review
  14. Article
  15. Endocytosis of Connexin 36 is Mediated by Interaction with Caveolin-1.International journal of molecular sciences · 2020
    Article
  16. Review
  17. Article
  18. Calmodulin-Mediated Regulation of Gap Junction Channels.International journal of molecular sciences · 2020
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Ryan C F SiuBiology Program, York University, Toronto ON, Canada.
Ekaterina SmirnovaChemistry Program, York University, Toronto ON, Canada.
Cherie A BrownBiology Program, York University, Toronto ON, Canada.
Christiane ZoidlBiology Program, York University, TorontoON, Canada; Psychology Program, York University, TorontoON, Canada.
David C SprayDominick P. Purpura Department of Neuroscience, Albert Einstein College of Medicine, New York NY, USA.
Logan W DonaldsonBiology Program, York University, Toronto ON, Canada.
Georg ZoidlBiology Program, York University, TorontoON, Canada; Psychology Program, York University, TorontoON, Canada.
York University · CAAlbert Einstein College of Medicine · US

Funding

Special Animal CoreP30DK041296 · NIDDK · YESHIVA UNIVERSITY · PI GUPTA, SANJEEV · 1989 to 2018
$22.9M
The Astrocyte Nexus: Cx43 Protein InteractionsR01NS092466 · NINDS · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI SCEMES, ELIANA, SPRAY, DAVID C · 2015 to 2019
$2.6M
NIDDK NIH HHS P30 DK041296NINDS NIH HHS R01 NS092466
6 · The paper itself

Abstract

Functional plasticity of neuronal gap junctions involves the interaction of the neuronal connexin36 with calcium/calmodulin-dependent kinase II (CaMKII). The important relationship between Cx36 and CaMKII must also be considered in the context of another protein partner, Ca

Indexed as

calmodulinCaMKIIconnexinselectrical synapseplasticityprotein interaction

Identifiers

PMID27917108
PMCPMC5114276
OpenAlexW2552704709

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.