Evidence map›Paper›PMID 27917076›Full record

ArticleGastroenterology & hepatology2016

The Cost-Effectiveness of Vedolizumab for Inflammatory Bowel Disease: A Review of the Current Literature.

Yecheskel Schneider, Monica Saumoy, Shirley Cohen-Mekelburg, Adam F Steinlauf, Ellen J Scherl

Open access · greenAbstract read
PubMed Full text at PMC
In one paragraph

Article in Gastroenterology & hepatology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Yecheskel SchneiderDr Schneider, Dr Saumoy, and Dr Cohen-Mekelburg are clinical fellows; Dr Steinlauf is an assistant professor of medicine; and Dr Scherl is a professor of clinical medicine in the Division of Gastroenterology and Hepatology at NewYork-Presbyterian/Weill Cornell Medical Center in New York, New York.
Monica SaumoyDr Schneider, Dr Saumoy, and Dr Cohen-Mekelburg are clinical fellows; Dr Steinlauf is an assistant professor of medicine; and Dr Scherl is a professor of clinical medicine in the Division of Gastroenterology and Hepatology at NewYork-Presbyterian/Weill Cornell Medical Center in New York, New York.
Shirley Cohen-MekelburgDr Schneider, Dr Saumoy, and Dr Cohen-Mekelburg are clinical fellows; Dr Steinlauf is an assistant professor of medicine; and Dr Scherl is a professor of clinical medicine in the Division of Gastroenterology and Hepatology at NewYork-Presbyterian/Weill Cornell Medical Center in New York, New York.
Adam F SteinlaufDr Schneider, Dr Saumoy, and Dr Cohen-Mekelburg are clinical fellows; Dr Steinlauf is an assistant professor of medicine; and Dr Scherl is a professor of clinical medicine in the Division of Gastroenterology and Hepatology at NewYork-Presbyterian/Weill Cornell Medical Center in New York, New York.
Ellen J ScherlDr Schneider, Dr Saumoy, and Dr Cohen-Mekelburg are clinical fellows; Dr Steinlauf is an assistant professor of medicine; and Dr Scherl is a professor of clinical medicine in the Division of Gastroenterology and Hepatology at NewYork-Presbyterian/Weill Cornell Medical Center in New York, New York.
Cornell University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The United States spends a greater share per gross domestic product on health care than any other developed country in the world. Cost-conscious, high-value care has an important role in the practice of medicine. Inflammatory bowel disease (IBD) affects 1.6 million people in the United States and is responsible for significant health care costs, with estimates as high as $31.6 billion annually, a large portion of which is attributable to the use of biologic therapies. As the number of therapeutic targets for IBD expands, gastroenterologists can anticipate the arrival of novel therapeutic agents on the market, and these may carry significant costs. Vedolizumab, a monoclonal antibody directed against the gut-selective integrin α4β7, is a novel biologic agent approved for the treatment of Crohn's disease and ulcerative colitis. Cost-effectiveness is an area of research that aims to assess the added value (in terms of both cost and utility) of diagnostic or therapeutic interventions. This article reviews the current literature evaluating the cost-effectiveness of vedolizumab for the treatment of IBD.

Indexed as

cost-effectivenessCrohn’s diseaseinflammatory bowel diseaseulcerative colitisVedolizumab

Identifiers

PMID27917076
PMCPMC5114504
OpenAlexW2569302771

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.