Evidence map›Paper›PMID 27916992›Full record

ArticleMolecular therapy : the journal of the American Society of Gene Therapy2016

Gene Editing for Duchenne Muscular Dystrophy Using the CRISPR/Cas9 Technology: The Importance of Fine-tuning the Approach.

Jacques P Tremblay, Jean-Paul Iyombe-Engembe, Benjamin Duchêne, Dominique L Ouellet

Abstract readLetter
In one paragraph

Article in Molecular therapy : the journal of the American Society of Gene Therapy, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. AAV9 Edits Muscle Stem Cells in Normal and Dystrophic Adult Mice.Molecular therapy : the journal of the American Society of Gene Therapy · 2019
    Article
  4. Canada'sFrontiers in medicine · 2019
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jacques P TremblayCentre de Recherche du CHU de Québec-Université Laval, Quebec, Quebec, Canada. Electronic address: Jacques-P.Tremblay@crchul.ulaval.ca.
Jean-Paul Iyombe-EngembeCentre de Recherche du CHU de Québec-Université Laval, Quebec, Quebec, Canada.
Benjamin DuchêneCentre de Recherche du CHU de Québec-Université Laval, Quebec, Quebec, Canada.
Dominique L OuelletCentre de Recherche du CHU de Québec-Université Laval, Quebec, Quebec, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

CRISPR-Cas SystemsGene EditingAnimalsClustered Regularly Interspaced Short Palindromic RepeatsDystrophinHumansMiceMice, Inbred mdxMuscular Dystrophy, DuchenneDystrophin

Identifiers

PMID27916992
PMCPMC5154487

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.