ArticleMedical science monitor : international medical journal of experimental and clinical research2016
Diagnostic Accuracy of Contrast-Enhanced Ultrasound Enhancement Patterns for Thyroid Nodules.
Article in Medical science monitor : international medical journal of experimental and clinical research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 4 of them syntheses that pooled it.
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Who cites it
31 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Performance of contrast-enhanced ultrasound (CEUS) in assessing thyroid nodules: a systematic review and meta-analysis using histological standard of reference.La Radiologia medica · 2020Pooled it
- Pooled it
- Comparative Diagnostic Accuracy of Contrast-Enhanced Ultrasound and Shear Wave Elastography in Differentiating Benign and Malignant Lesions: A Network Meta-Analysis.Frontiers in oncology · 2019Pooled it
- Pooled it
- Conventional ultrasound combined with contrast-enhanced ultrasound for differentiating benign and malignant thyroid nodules.Quantitative imaging in medicine and surgery · 2026Article
- Development and validation of a nomogram based on conventional and contrast-enhanced ultrasound for differentiating malignant from benign thyroid nodules.Quantitative imaging in medicine and surgery · 2025Article
- Value of dynamic contrast-enhanced ultrasound in predicting cervical lymph node metastasis in papillary thyroid carcinoma patients with Hashimoto's thyroiditis.Gland surgery · 2025Article
- Additional diagnostic value of ratio indices of quantitative contrast-enhanced ultrasound parameters in small solid C-TIRADS 4 thyroid nodules.Frontiers in oncology · 2025Article
- Sonographic characteristics of thyroid nodules with a Halo.Thyroid research · 2024Article
- Diagnostic efficacy of the contrast-enhanced ultrasound thyroid imaging reporting and data system classification for benign and malignant thyroid nodules.Quantitative imaging in medicine and surgery · 2024Article
- Performance of Intraoperative Contrast-Enhanced Ultrasound (Io-CEUS) in the Diagnosis of Primary Lung Cancer.Diagnostics (Basel, Switzerland) · 2024Article
- Diagnostic efficacy of data mining method based on multimodal ultrasound for papillary thyroid carcinoma.Frontiers in oncology · 2024Article
- Using multimodal ultrasound including full-time-series contrast-enhanced ultrasound cines for identifying the nature of thyroid nodules.Frontiers in oncology · 2024Article
- Combining CEUS and ultrasound parameters in thyroid nodule and cancer diagnosis: a TIRADS-based evaluation.Frontiers in endocrinology · 2024Article
- Applying machine-learning models to differentiate benign and malignant thyroid nodules classified as C-TIRADS 4 based on 2D-ultrasound combined with five contrast-enhanced ultrasound key frames.Frontiers in endocrinology · 2024Article
- Article
- Analysis and prediction of regrowth in benign thyroid nodules undergoing radiofrequency ablation: a retrospective study with a 5-year follow-up.European radiology · 2023Article
- Aggressive primary thyroid lymphoma invading the internal jugular vein: a case series.Quantitative imaging in medicine and surgery · 2023Article
- Value of CEUS features in diagnosing thyroid nodules with halo sign on B-mode ultrasound.BMC medical imaging · 2023Article
- Adult-type rhabdomyoma of the thyroid: A case report.Frontiers in oncology · 2023Article
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND The aim of this study was to investigate the accuracy of contrast-enhanced ultrasound (CEUS) enhancement patterns in the assessment of thyroid nodules. MATERIAL AND METHODS A total of 158 patients with suspected thyroid cancer underwent conventional ultrasound (US) and CEUS examinations. The contrast enhancement patterns of the lesions, including the peripheries of the lesions, were assessed by CEUS scans. The relationship between the size of the lesions and the degree of enhancement was also studied. US- and/or CEUS-guided biopsy was used to obtain specimens for histopathological diagnosis. RESULTS The final data included 148 patients with 157 lesions. Seventy-five patients had 82 malignant lesions and 73 patients had 75 benign lesions. Peripheral ring enhancement was seen in 40 lesions. The differences of enhancement patterns and peripheral rings between benign and malignant nodules were significant (p=0.000, 0.000). The diagnostic sensitivity, specificity, and accuracy for malignant were 88%, 65.33%, and 88.32%, respectively, for CEUS, whereas they were 98.33%, 42.67%, and 71.97%, respectively, for TC by conventional US. The misdiagnosis rate by conventional US was 57.33% and 34.67% by CEUS (p=0.005). With regard to the size of lesions, a significant difference was found between low-enhancement, iso-enhancement, high-enhancement, iso-enhancement with no-enhancement area and no-enhancement (p=0.000). CONCLUSIONS In patients with suspicious US characteristics, CEUS had high specificity and contributed to establishing the diagnosis. Therefore, CEUS could avoid unnecessary biopsy.
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