Evidence map›Paper›PMID 27916916›Full record

ArticleInternational journal of environmental research and public health2016

Aniline Induces Oxidative Stress and Apoptosis of Primary Cultured Hepatocytes.

Yue Wang, Hong Gao, Xiao-Lin Na, Shu-Ying Dong, Hong-Wei Dong, Jia Yu, Li Jia, Yong-Hui Wu

Open access · goldAbstract read
In one paragraph

Article in International journal of environmental research and public health, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 41 citations in OpenAlex.

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  15. Application ofFrontiers in pharmacology · 2019
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Yue WangDepartment of Occupational Health, College of Public Health, Harbin Medical University, Harbin 150086, China. wangyue5056@163.com.
Hong GaoDepartment of Sanitary Microorganisms, College of Public Health, Harbin Medical University, Harbin 150086, China. m15114515383@163.com.
Xiao-Lin NaDepartment of Environmental Health, College of Public Health, Harbin Medical University, Harbin 150086, China. jljz5858@163.com.
Shu-Ying DongDepartment of Environmental Health, College of Public Health, Harbin Medical University, Harbin 150086, China. dong.shuying@163.com.
Hong-Wei DongDepartment of Occupational Health, College of Public Health, Harbin Medical University, Harbin 150086, China. donghongwei0824@163.com.
Jia YuDepartment of Environmental Health, College of Public Health, Harbin Medical University, Harbin 150086, China. jiali1013@126.com.
Li JiaDepartment of Environmental Health, College of Public Health, Harbin Medical University, Harbin 150086, China. jiali1013@163.com.
Yong-Hui WuDepartment of Occupational Health, College of Public Health, Harbin Medical University, Harbin 150086, China. wuyonghui777@163.com.
Harbin Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The toxicity and carcinogenicity of aniline in humans and animals have been well documented. However, the molecular mechanism involved in aniline-induced liver toxicity and carcinogenesis remains unclear. In our research, primary cultured hepatocytes were exposed to aniline (0, 1.25, 2.50, 5.0 and 10.0 μg/mL) for 24 h in the presence or absence of

Indexed as

AcetylcysteineAniline CompoundsAnimalsApoptosisCatalaseCells, CulturedCell SurvivalEnvironmental PollutantsGlutathioneHepatocytesHumansMaleMalondialdehydeMembrane Potential, MitochondrialOxidation-ReductionOxidative StressAcetylcysteineanilineAniline CompoundsCatalaseEnvironmental PollutantsGlutathioneMalondialdehydeReactive Oxygen SpeciesSuperoxide Dismutaseanilineapoptosishepatocytesreactive oxygen species

Identifiers

PMID27916916
PMCPMC5201329
OpenAlexW2558958398

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.