Evidence map›Paper›PMID 27916902›Full record

ArticleMolecules (Basel, Switzerland)2016

Synthesis and Biological Evaluation of Novel Aromatic Imide-Polyamine Conjugates.

Ming Li, Yuxia Wang, Jianying Zhang, Songqiang Xie, Chaojie Wang, Yingliang Wu

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Polyamine-Drug Conjugates: Do They Boost Drug Activity?Molecules (Basel, Switzerland) · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ming LiDepartment of Pharmacology, Shenyang Pharmaceutical University, Shenyang 110016, China. songxu666@163.com.
Yuxia WangCollege of Chemistry and Chemical Engineering, Henan University, Kaifeng 475001, China. wangyuxia@henu.edu.cn.
Jianying ZhangPharmaceutical College, Henan University, Kaifeng 475001, China. 18237878517@163.com.
Songqiang XiePharmaceutical College, Henan University, Kaifeng 475001, China. xiesq@henu.edu.cn.
Chaojie WangKey Laboratory of Natural Medicine and Immuno-Engineering, Kaifeng 475001, China. wcjsxq@henu.edu.cn.
Yingliang WuDepartment of Pharmacology, Shenyang Pharmaceutical University, Shenyang 110016, China. yingliang_1016@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Three types of conjugates in which aromatic imide scaffolds were coupled to diverse amine/polyamine motifs were synthesized, and their antitumor activities were evaluated in vitro and in vivo. Results showed that the conjugate

Indexed as

AnimalsAntineoplastic AgentsApoptosisCell Line, TumorCell ProliferationHumansImidesLiver Neoplasms, ExperimentalLung NeoplasmsMaleMicePolyaminesXenograft Model Antitumor AssaysAntineoplastic AgentsImidesPolyaminesamonafideantitumornaphthalimidepolyaminesynthesis

Identifiers

PMID27916902
PMCPMC6273765

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.