Evidence map›Paper›PMID 27916838›Full record

ArticleInternational journal of molecular sciences2016

Prognostic Relevance of Methylenetetrahydrofolate Reductase Polymorphisms for Prostate Cancer.

Victor C Lin, Te-Ling Lu, Hsin-Ling Yin, Sheau-Fang Yang, Yung-Chin Lee, Chia-Chu Liu, Chao-Yuan Huang, Chia-Cheng Yu, Ta-Yuan Chang, Shu-Pin Huang and 1 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.6field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Oncotarget · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 1 country.

Victor C LinDepartment of Urology, E-Da Hospital, Kaohsiung 824, Taiwan. victorlin0098@yahoo.com.tw.
Te-Ling LuDepartment of Pharmacy, China Medical University, Taichung 404, Taiwan. lutl@mail.cmu.edu.tw.
Hsin-Ling YinDepartment of Pathology, Kaohsiung Medical University Hospital, Kaohsiung 807, Taiwan. schoolyin@gmail.com.
Sheau-Fang YangDepartment of Pathology, Kaohsiung Medical University Hospital, Kaohsiung 807, Taiwan. sfyang@kmu.edu.tw.
Yung-Chin LeeDepartment of Urology, Kaohsiung Medical University Hospital, Kaohsiung 807, Taiwan. leeyc12345@yahoo.com.tw.
Chia-Chu LiuDepartment of Urology, Kaohsiung Medical University Hospital, Kaohsiung 807, Taiwan. m8201055@yahoo.com.tw.
Chao-Yuan HuangDepartment of Urology, National Taiwan University Hospital, College of Medicine, National Taiwan University, Taipei 100, Taiwan. cyhuang0909@ntu.edu.tw.
Chia-Cheng YuDivision of Urology, Department of Surgery, Kaohsiung Veterans General Hospital, Kaohsiung 813, Taiwan. ccyu@vghks.gov.tw.
Ta-Yuan ChangDepartment of Occupational Safety and Health, China Medical University, Taichung 404, Taiwan. tychang@mail.cmu.edu.tw.
Shu-Pin HuangDepartment of Urology, Kaohsiung Medical University Hospital, Kaohsiung 807, Taiwan. shpihu@yahoo.com.tw.
Bo-Ying BaoDepartment of Pharmacy, China Medical University, Taichung 404, Taiwan. bao@mail.cmu.edu.tw.
Kaohsiung Medical University · TWChina Medical University · TWAsia University · TWE-Da Hospital · TWNational Taiwan University Hospital · TWNational Yang Ming Chiao Tung University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Folate metabolism has been associated with cancers via alterations in nucleotide synthesis, DNA methylation, and DNA repair. We hypothesized that genetic variants in methylenetetrahydrofolate reductase (

Indexed as

Genetic Predisposition to DiseaseGenotypeHaplotypesHumansMaleMethylenetetrahydrofolate Reductase (NADPH2)Neoplasm Recurrence, LocalPolymorphism, GeneticPolymorphism, Single NucleotidePrognosisProstatectomyProstatic NeoplasmsMethylenetetrahydrofolate Reductase (NADPH2)genetic variationmethylenetetrahydrofolate reductaseprostate cancerradical prostatectomyrecurrence

Identifiers

PMID27916838
PMCPMC5187796
OpenAlexW2558971275

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.