Evidence map›Paper›PMID 27916811›Full record

ArticleMolecules (Basel, Switzerland)2016

Design, Synthesis and Biological Evaluation of Novel Primaquine-Cinnamic Acid Conjugates of the Amide and Acylsemicarbazide Type.

Kristina Pavić, Ivana Perković, Petra Gilja, Filip Kozlina, Katja Ester, Marijeta Kralj, Dominique Schols, Dimitra Hadjipavlou-Litina, Eleni Pontiki, Branka Zorc

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
6.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 32 citations in OpenAlex.

  1. Article
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  3. Synthesis of Ursolic Acid-based Hybrids:Recent advances in anti-infective drug discovery · 2024
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  5. Insights into Antimalarial Activity ofMolecules (Basel, Switzerland) · 2022
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Review
  12. Primaquine derivatives: Modifications of the terminal amino group.European journal of medicinal chemistry · 2019
    Review
  13. Article
  14. Article
  15. Insights into biological activity of ureidoamides with primaquine and amino acid moieties.Journal of enzyme inhibition and medicinal chemistry · 2018
    Article
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 3 countries.

Kristina PavićFaculty of Pharmacy and Biochemistry, University of Zagreb, A. Kovačića 1, HR-10 000 Zagreb, Croatia. kpavic@pharma.hr.
Ivana PerkovićFaculty of Pharmacy and Biochemistry, University of Zagreb, A. Kovačića 1, HR-10 000 Zagreb, Croatia. iperkovic@pharma.hr.
Petra GiljaFaculty of Pharmacy and Biochemistry, University of Zagreb, A. Kovačića 1, HR-10 000 Zagreb, Croatia. pgilja@student.pharma.hr.
Filip KozlinaFaculty of Pharmacy and Biochemistry, University of Zagreb, A. Kovačića 1, HR-10 000 Zagreb, Croatia. filip.kozlina@gmail.com.
Katja EsterDivision of Molecular Medicine, Rudjer Bošković Institute, Bijenička cesta 54, HR-10 000 Zagreb, Croatia. katja.ester@irb.hr.
Marijeta KraljDivision of Molecular Medicine, Rudjer Bošković Institute, Bijenička cesta 54, HR-10 000 Zagreb, Croatia. marijeta.kralj@irb.hr.
Dominique ScholsRega Institute for Medical Research, Katholieke Universiteit Leuven, Minderbroedersstraat 10, B-3000 Leuven, Belgium. dominique.schols@rega.kuleuven.be.
Dimitra Hadjipavlou-LitinaFaculty of Health Sciences, School of Pharmacy, Aristotles University of Thessaloniki, Thessaloniki 54 124, Greece. hadjipav@pharm.auth.gr.
Eleni PontikiFaculty of Health Sciences, School of Pharmacy, Aristotles University of Thessaloniki, Thessaloniki 54 124, Greece. epontiki@pharm.auth.gr.
Branka ZorcFaculty of Pharmacy and Biochemistry, University of Zagreb, A. Kovačića 1, HR-10 000 Zagreb, Croatia. bzorc@pharma.hr.
University of Zagreb · HRAristotle University of Thessaloniki · GRRuđer Bošković Institute · HRRega Institute for Medical Research · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this paper design and synthesis of a scaffold comprising primaquine (PQ) motif and cinnamic acid derivatives (CADs) bound directly (compounds

Indexed as

AdenoviridaeAnimalsAntineoplastic AgentsAntioxidantsAntiviral AgentsCell Line, TumorCinnamatesCoronavirusHeLa CellsHerpesvirus 1, HumanHerpesvirus 2, HumanHumansMCF-7 CellsMiceNeoplasmsPrimaquineAntineoplastic AgentsAntioxidantsAntiviral AgentsCinnamatescinnamic acidPrimaquineantioxidative activityantiviral activitycinnamic acid derivativeconjugatecytostatic activityprimaquine

Identifiers

PMID27916811
PMCPMC6273687
OpenAlexW2557699920

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.