Evidence map›Paper›PMID 27916618›Full record

ArticleChest2017

Perceived Discrimination Associated With Asthma and Related Outcomes in Minority Youth: The GALA II and SAGE II Studies.

Neeta Thakur, Nicolas E Barcelo, Luisa N Borrell, Smriti Singh, Celeste Eng, Adam Davis, Kelley Meade, Michael A LeNoir, Pedro C Avila, Harold J Farber and 8 more

Open access · bronzeAbstract read
In one paragraph

Article in Chest, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
53citing papers in PubMed, 1 pooled it
27.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

53 citing papers in PubMed, 1 synthesis or guideline pooled it, 92 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
  4. Influence of social support on asthma self-management in adolescents.The Journal of asthma : official journal of the Association for the Care of Asthma · 2021
    Trial
  5. Observational
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Managing childhood asthma with an eye toward environmental, social, and behavioral features.Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology · 2025
    Review
  12. Article
  13. Review
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Questions in Mild Asthma: An Official American Thoracic Society Research Statement.American journal of respiratory and critical care medicine · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 12 institutions in 2 countries.

Neeta ThakurDepartment of Medicine, University of California, San Francisco, San Francisco.
Nicolas E BarceloDepartment of Medicine, University of California, San Francisco, San Francisco.
Luisa N BorrellDepartment of Epidemiology and Biostatistics, Graduate School of Public Health and Health Policy, City University of New York, New York. Electronic address: luisa.borrell@sph.cuny.edu.
Smriti SinghDepartment of Medicine, University of California, San Francisco, San Francisco.
Celeste EngDepartment of Medicine, University of California, San Francisco, San Francisco.
Adam DavisChildren's Hospital Oakland Research Institute, UCSF Benioff Children's Hospital, Oakland, CA.
Kelley MeadeChildren's Hospital Oakland Research Institute, UCSF Benioff Children's Hospital, Oakland, CA.
Michael A LeNoirBay Area Pediatrics, Oakland, CA.
Pedro C AvilaDepartment of Medicine, Northwestern University, Chicago, IL.
Harold J FarberDepartment of Pediatrics, Section of Pulmonology, Baylor College of Medicine and Texas Children's Hospital, Houston, TX.
Denise SerebriskyPediatric Pulmonary Division, Jacobi Medical Center, Bronx, NY.
Emerita Brigino-BuenaventuraDepartment of Allergy and Immunology, Kaiser Permanente Vallejo Medical Center, Vallejo.
William Rodriguez-CintronVeterans Caribbean Health Care System, San Juan, Puerto Rico.
Shannon ThyneDepartment of Pediatrics, University of California, Los Angeles, Los Angeles, CA.
Jose R Rodriguez-SantanaCentro de Neumología Pediátrica, San Juan, Puerto Rico.
Saunak SenDepartment of Preventive Medicine, University of Tennessee Health Science Center, Memphis, TN.
Kirsten Bibbins-DomingoDepartment of Medicine, University of California, San Francisco, San Francisco.
Esteban Gonzalez BurchardDepartment of Medicine, University of California, San Francisco, San Francisco; Department of Bioengineering and Therapeutic Sciences, University of California, San Francisco, San Francisco.
University of California, San Francisco · USUCSF Benioff Children's Hospital · USCentro de Neumologia Pediatrica · PRCity University of New York · USJacobi Medical Center · USKaiser Permanente Vallejo Medical Center · USKIPP Bay Area Schools · USNorthwestern University · USTexas Children's Hospital · USUniversity of California, Los Angeles · USUniversity of Tennessee Health Science Center · USVA Caribbean Healthcare System · PR

Funding

Understanding Asthma EndotypesU19AI077439 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI David J Erle · 2008 to 2026
$41.1M
ZOLENDRONIC ACID IN CHILDREN W/ SEVERE OSTEOGENESIS IMPERFECTAM01RR000188 · NCRR · BAYLOR COLLEGE OF MEDICINE · PI SHEARER, WILLIAM THOMAS · 1985 to 2011
$30.6M
New Approaches for Empowering Studies of Asthma in Populations of African DescentR01HL104608 · NHLBI · UNIVERSITY OF COLORADO DENVER · PI BARNES, KATHLEEN C, KENNY, EIMEAR ELIZABETH · 2011 to 2022
$23.1M
WELFARE REFORM AND THE PERINATAL HEALTH OF IMMIGRANTSM01RR000083 · NCRR · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI KESSLER, DAVID A · 1985 to 2006
$21.1M
CLINICAL, PHARMACOLOGY, DRUG ACTION &PHARMACOKINETICST32GM007546 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Radojka Savic · 1985 to 2026
$8.9M
Social Interventions to address disparities In young adult tobacco useP60MD006902 · NIMHD · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI BIBBINS-DOMINGO, KIRSTEN · 2012 to 2016
$6.4M
Gene-environments and Admixture in Latino Asthmatics (GALA 2)R01ES015794 · NIEHS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI BURCHARD, ESTEBAN GONZALEZ · 2008 to 2012
$5.4M
Whole Genome Analyses for Asthma in Latino PopulationsR01HL088133 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI BURCHARD, ESTEBAN GONZALEZ · 2008 to 2012
$3.8M
Genes, air pollution, and asthma severity in minority childrenR01MD010443 · NIMHD · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI SEIBOLD, MAX A, ZIV, ELAD · 2016 to 2020
$3.8M
Epigenomics of asthma risk factors and clinical subtypes in minority childrenR01HL155024 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI BORRELL, LUISA N, ZAITLEN, NOAH A · 2021 to 2024
$2.9M
Case-control Association Studies and Genetic ConfoundingR01HL078885 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI BURCHARD, ESTEBAN GONZALEZ · 2005 to 2009
$1.9M
Promoting Research Opportunities Fully--Prospective Academics Transforming HealthR25MD006832 · NIMHD · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI ARONSON, LOUISE, FERNANDEZ, ALICIA · 2011 to 2015
$1.7M
NCRR NIH HHS M01 RR000083NCRR NIH HHS M01 RR000188NHLBI NIH HHS K12 HL119997NHLBI NIH HHS K23 HL125551NHLBI NIH HHS R01 HL078885NHLBI NIH HHS R01 HL088133NHLBI NIH HHS R01 HL104608NHLBI NIH HHS R01 HL155024NIAID NIH HHS U19 AI077439NIEHS NIH HHS R01 ES015794NIEHS NIH HHS R21 ES024844NIGMS NIH HHS T32 GM007546NIMHD NIH HHS P60 MD006902NIMHD NIH HHS R01 MD010443NIMHD NIH HHS R25 MD006832
6 · The paper itself

Abstract

backgroundAsthma disproportionately affects minority populations and is associated with psychosocial stress such as racial/ethnic discrimination. We aimed to examine the association of perceived discrimination with asthma and poor asthma control in African American and Latino youth.

methodsWe included African American (n = 954), Mexican American (n = 1,086), other Latino (n = 522), and Puerto Rican Islander (n = 1,025) youth aged 8 to 21 years from the Genes-Environments and Admixture in Latino Americans study and the Study of African Americans, Asthma, Genes, and Environments. Asthma was defined by physician diagnosis, and asthma control was defined based on the National Heart, Lung, and Blood Institute guidelines. Perceived racial/ethnic discrimination was assessed by the Experiences of Discrimination questionnaire, with a focus on school, medical, and public settings. We examined the associations of perceived discrimination with each outcome and whether socioeconomic status (SES) and global African ancestry modified these associations.

resultsAfrican American children reporting any discrimination had a 78% greater odds of experiencing asthma (OR, 1.78; 95% CI, 1.33-2.39) than did those not reporting discrimination. Similarly, African American children faced increased odds of poor asthma control with any experience of discrimination (OR, 1.97; 95% CI, 1.42-2.76) over their counterparts not reporting discrimination. These associations were not observed among Latino children. We observed heterogeneity of the association between reports of discrimination and asthma according to SES, with reports of discrimination increasing the odds of having asthma among low-SES Mexican American youth (interaction P = .01) and among high-SES other Latino youth (interaction P = .04).

conclusionsPerceived discrimination is associated with increased odds of asthma and poorer control among African American youth. SES exacerbates the effect of perceived discrimination on having asthma among Mexican American and other Latino youth.

Indexed as

RacismAdolescentAsthmaBlack or African AmericanCase-Control StudiesChildFemaleHealth Status DisparitiesHispanic or LatinoHumansMaleRisk FactorsSocial ClassStress, PsychologicalSurveys and QuestionnairesUnited Stateschildrenhealth status disparitypsychosocial stressracesocioeconomic status

Identifiers

PMID27916618
PMCPMC5472516
OpenAlexW2557611028

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.