Evidence map›Paper›PMID 27916543›Full record

ArticleDiagnostic microbiology and infectious disease2017

Rapid assessment of tetanus vaccine-induced immunity in Bangladesh and the Gambia.

Girija Ramakrishnan, Marcia Wright, Masud Alam, Caitlin Naylor, Mamun Kabir, Ayesha Zerin, Tahsin Ferdous, Karl Pedersen, Branwen J Hennig, Jeffrey R Donowitz and 5 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Diagnostic microbiology and infectious disease, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Trial
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 7 institutions in 4 countries.

Girija RamakrishnanDepartment of Medicine/Division of Infectious Disease and International Health, University of Virginia, Charlottesville, VA, USA.
Marcia WrightTechLab Inc., Blacksburg, VA, USA.
Masud AlamInternational Centre for Diarrhoeal Disease Research, Bangladesh, Dhaka, Bangladesh (icddr,b).
Caitlin NaylorNutrition Theme, MRC Unit The Gambia (MRCG), Banjul, The Gambia.
Mamun KabirInternational Centre for Diarrhoeal Disease Research, Bangladesh, Dhaka, Bangladesh (icddr,b).
Ayesha ZerinInternational Centre for Diarrhoeal Disease Research, Bangladesh, Dhaka, Bangladesh (icddr,b).
Tahsin FerdousInternational Centre for Diarrhoeal Disease Research, Bangladesh, Dhaka, Bangladesh (icddr,b).
Karl PedersenTechLab Inc., Blacksburg, VA, USA.
Branwen J HennigNutrition Theme, MRC Unit The Gambia (MRCG), Banjul, The Gambia; MRC International Nutrition Group, London, School of Hygiene & Tropical Medicine, London, UK.
Jeffrey R DonowitzDivision of Pediatric Infectious Diseases, Children's Hospital of Richmond at Virginia Commonwealth University, Richmond.
Rita WegmullerNutrition Theme, MRC Unit The Gambia (MRCG), Banjul, The Gambia; MRC International Nutrition Group, London, School of Hygiene & Tropical Medicine, London, UK.
Rashidul HaqueInternational Centre for Diarrhoeal Disease Research, Bangladesh, Dhaka, Bangladesh (icddr,b).
William A PetriDepartment of Medicine/Division of Infectious Disease and International Health, University of Virginia, Charlottesville, VA, USA.
Joel HerbeinTechLab Inc., Blacksburg, VA, USA.
Carol A GilchristDepartment of Medicine/Division of Infectious Disease and International Health, University of Virginia, Charlottesville, VA, USA. Electronic address: cg2p@eservices.virginia.edu.
International Centre for Diarrhoeal Disease Research · BDTechLab (United States) · USLondon School of Hygiene & Tropical Medicine · GBUniversity of Virginia · USMRC Unit the Gambia · GMUniversity of Virginia Health System · USVirginia Commonwealth University · US

Funding

FIELD STUDIES OF IMMUNITY TO AMEBIASIS IN BANGLADESHR01AI043596 · NIAID · UNIVERSITY OF VIRGINIA CHARLOTTESVILLE · PI CAROL A GILCHRIST, William A Petri · 1998 to 2026
$7.7M
NIAID NIH HHS R01 AI043596
6 · The paper itself

Abstract

We have developed recombinant fragment C based rapid point of care dipstick devices to assess tetanus immunization status using plasma or whole blood. The devices demonstrated specificity of 0.90 and sensitivity of 0.90 (whole blood)/0.94 (plasma) at field sites in Bangladesh and The Gambia when compared to a commercial ELISA with the immune cut-off titer set as ≥0.1IU/mL.

Indexed as

AdultAntibodies, BacterialBangladeshChildGambiaHumansMalePeptide FragmentsRecombinant ProteinsSensitivity and SpecificityTetanusTetanus ToxinTetanus ToxoidVaccinationAntibodies, BacterialPeptide FragmentsRecombinant ProteinsTetanus Toxintetanus toxin fragment CTetanus ToxoidDipstickFragment CLateral flowTetanusVaccine

Identifiers

PMID27916543
PMCPMC5292284
OpenAlexW2554264787

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.