Evidence map›Paper›PMID 27916531›Full record

ArticleCell metabolism2016

Dietary Restriction Extends the Lifespan of Circadian Mutants tim and per.

Matt Ulgherait, Anna Chen, Miles K Oliva, Han X Kim, Julie C Canman, William W Ja, Mimi Shirasu-Hiza

Abstract readLetterComment
In one paragraph

Article in Cell metabolism, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Trial
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. International journal of molecular sciences · 2020
    Review
  8. Review
  9. Article
  10. Review
  11. Review
  12. Aging and the clock: Perspective from flies to humans.The European journal of neuroscience · 2020
    Review
  13. Article
  14. Article
  15. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Matt UlgheraitDepartment of Genetics and Development, Columbia University Medical Center, New York, NY 10032, USA.
Anna ChenDepartment of Biological Sciences, Columbia University, New York, NY 10025, USA.
Miles K OlivaDepartment of Biological Sciences, Columbia University, New York, NY 10025, USA.
Han X KimDepartment of Genetics and Development, Columbia University Medical Center, New York, NY 10032, USA; Department of Pathology and Cell Biology, Columbia University Medical Center, New York, NY 10032, USA.
Julie C CanmanDepartment of Pathology and Cell Biology, Columbia University Medical Center, New York, NY 10032, USA.
William W JaDepartment of Metabolism and Aging, The Scripps Research Institute, Jupiter, FL 33458, USA.
Mimi Shirasu-HizaDepartment of Genetics and Development, Columbia University Medical Center, New York, NY 10032, USA. Electronic address: ms4095@cumc.columbia.edu.

Funding

Hormones: Molecular Mechanism of Action and FunctionsT32DK007328 · NIDDK · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI KOUSTENI, STAVROULA · 1986 to 2025
$7.8M
Circadian-Regulated Aging PhysiologiesR01AG045842 · NIA · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI Michele M Shirasu-Hiza · 2013 to 2026
$5.1M
Cell type-variation of cytokinesisR01GM117407 · NIGMS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI CANMAN, JULIE C · 2016 to 2023
$2.9M
IR-LAMP: Optigenetic technology to spatially manipulate protein function in vivoDP2OD008773 · OD · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI CANMAN, JULIE C · 2011 to 2011
$2.4M
Nutritional and Epigenetic Priming of Metabolism and Aging in DrosophilaR01AG045036 · NIA · SCRIPPS FLORIDA · PI JA, WILLIAM W · 2014 to 2018
$2.0M
Circadian regulation of phagocytosisR01GM105775 · NIGMS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI SHIRASU-HIZA, MICHELE M · 2013 to 2017
$1.6M
NIA NIH HHS R01 AG045036NIA NIH HHS R01 AG045842NIDDK NIH HHS T32 DK007328NIGMS NIH HHS R01 GM105775NIGMS NIH HHS R01 GM117407NIH HHS DP2 OD008773
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Drosophila melanogasterDrosophila ProteinsAnimalsCircadian RhythmDrosophilaNuclear ProteinsPeriod Circadian ProteinsDrosophila ProteinsNuclear ProteinsPeriod Circadian Proteinsagingcircadian rhythmclockdietary restrictionlifespanlongevitymetabolismpdfperiodtimeless

Identifiers

PMID27916531
PMCPMC5356364

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.