Evidence map›Paper›PMID 27915452›Full record

ArticleNaunyn-Schmiedeberg's archives of pharmacology2017

Chronic enalapril treatment increases transient outward potassium current in cardiomyocytes isolated from right ventricle of spontaneously hypertensive rats.

Luiz Fernando Rodrigues Junior, Ana Carolina de Azevedo Carvalho, Enildo Broetto Pimentel, José Geraldo Mill, José Hamilton Matheus Nascimento

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in Naunyn-Schmiedeberg's archives of pharmacology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Luiz Fernando Rodrigues JuniorInstitute of Biophysics Carlos Chagas Filho, Laboratory of Cardiac Electrophysiology Antonio Paes de Carvalho, Federal University of Rio de Janeiro, Av. Carlos Chagas Filho, 373 - CCS Bloco G - Ilha do Fundao, 21, Rio de Janeiro, RJ, 941-902, Brazil.
Ana Carolina de Azevedo CarvalhoInstitute of Biophysics Carlos Chagas Filho, Laboratory of Cardiac Electrophysiology Antonio Paes de Carvalho, Federal University of Rio de Janeiro, Av. Carlos Chagas Filho, 373 - CCS Bloco G - Ilha do Fundao, 21, Rio de Janeiro, RJ, 941-902, Brazil.
Enildo Broetto PimentelDepartment of Physiological Sciences, Federal University of Espírito Santo, Vitória, Brazil.
José Geraldo MillDepartment of Physiological Sciences, Federal University of Espírito Santo, Vitória, Brazil.
José Hamilton Matheus NascimentoInstitute of Biophysics Carlos Chagas Filho, Laboratory of Cardiac Electrophysiology Antonio Paes de Carvalho, Federal University of Rio de Janeiro, Av. Carlos Chagas Filho, 373 - CCS Bloco G - Ilha do Fundao, 21, Rio de Janeiro, RJ, 941-902, Brazil. jhmn@biof.ufrj.br.
Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro · BRUniversidade Federal do Espírito Santo · BRUniversidade Federal do Estado do Rio de Janeiro · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

It has been well established that chronic pressure overload resulting from hypertension leads to ventricular hypertrophy and electrophysiological remodeling. The transient outward potassium current (I

Indexed as

Angiotensin-Converting Enzyme InhibitorsAnimalsAntihypertensive AgentsBlood PressureCardiomegalyDisease Models, AnimalElectric CapacitanceEnalaprilHeart VentriclesHydralazineHypertensionMaleMembrane PotentialsMyocytes, CardiacPotassiumPotassium ChannelsAngiotensin-Converting Enzyme InhibitorsAntihypertensive AgentsEnalaprilHydralazinePotassiumPotassium ChannelsVasodilator AgentsAngiotensin-converting enzyme inhibitorsEnalaprilHypertensionHypertrophySHRTransient outward potassium current

Identifiers

PMID27915452
OpenAlexW2558937383

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.