Evidence map›Paper›PMID 27915230›Full record

ArticleNucleic acids research2017

PHI-base: a new interface and further additions for the multi-species pathogen-host interactions database.

Martin Urban, Alayne Cuzick, Kim Rutherford, Alistair Irvine, Helder Pedro, Rashmi Pant, Vidyendra Sadanadan, Lokanath Khamari, Santoshkumar Billal, Sagar Mohanty and 1 more

Open access · goldAbstract read
In one paragraph

Article in Nucleic acids research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 122 papers.

0numbers the graph read from it
0cells of the map it votes in
122citing papers in PubMed
12.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

122 citing papers in PubMed, 245 citations in OpenAlex.

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  17. A Relationship Prediction Method forJournal of fungi (Basel, Switzerland) · 2023
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  18. Verticillium longisporum phospholipase VlsPLAMolecular plant pathology · 2023
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  19. The Adaptation ofJournal of fungi (Basel, Switzerland) · 2023
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  20. Article

62 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Martin UrbanDepartment of Plant Biology and Crop Science, Rothamsted Research, Harpenden, Hertfordshire AL5 2JQ, UK Martin.Urban@rothamsted.ac.uk.
Alayne CuzickDepartment of Plant Biology and Crop Science, Rothamsted Research, Harpenden, Hertfordshire AL5 2JQ, UK.
Kim RutherfordCambridge Systems Biology and Department of Biochemistry, University of Cambridge, Sanger Building, 80 Tennis Court Road, Cambridge, Cambridgeshire CB2 1GA, UK.
Alistair IrvineDepartment of Plant Biology and Crop Science, Rothamsted Research, Harpenden, Hertfordshire AL5 2JQ, UK.
Helder PedroThe European Molecular Biology Laboratory, The European Bioinformatics Institute, Hinxton, Cambridgeshire CB10 1SD, UK.ORCID 0000-0001-7582-1565
Rashmi PantMolecular Connections Private Limited, Basavanagudi, Bangalore 560 004, India.
Vidyendra SadanadanMolecular Connections Private Limited, Basavanagudi, Bangalore 560 004, India.
Lokanath KhamariMolecular Connections Private Limited, Basavanagudi, Bangalore 560 004, India.
Santoshkumar BillalMolecular Connections Private Limited, Basavanagudi, Bangalore 560 004, India.
Sagar MohantyMolecular Connections Private Limited, Basavanagudi, Bangalore 560 004, India.
Kim E Hammond-KosackDepartment of Plant Biology and Crop Science, Rothamsted Research, Harpenden, Hertfordshire AL5 2JQ, UK Kim.Hammond-Kosack@rothamsted.ac.uk.
Rothamsted Research · GBEuropean Bioinformatics Institute · GBUniversity of Cambridge · GB

Funding

Biotechnology and Biological Sciences Research Council BB/I/001077/1Biotechnology and Biological Sciences Research Council BB/J/004383/1Biotechnology and Biological Sciences Research Council BB/K020056/1
6 · The paper itself

Abstract

The pathogen-host interactions database (PHI-base) is available at www.phi-base.org PHI-base contains expertly curated molecular and biological information on genes proven to affect the outcome of pathogen-host interactions reported in peer reviewed research articles. In addition, literature that indicates specific gene alterations that did not affect the disease interaction phenotype are curated to provide complete datasets for comparative purposes. Viruses are not included. Here we describe a revised PHI-base Version 4 data platform with improved search, filtering and extended data display functions. A PHIB-BLAST search function is provided and a link to PHI-Canto, a tool for authors to directly curate their own published data into PHI-base. The new release of PHI-base Version 4.2 (October 2016) has an increased data content containing information from 2219 manually curated references. The data provide information on 4460 genes from 264 pathogens tested on 176 hosts in 8046 interactions. Prokaryotic and eukaryotic pathogens are represented in almost equal numbers. Host species belong ∼70% to plants and 30% to other species of medical and/or environmental importance. Additional data types included into PHI-base 4 are the direct targets of pathogen effector proteins in experimental and natural host organisms. The curation problems encountered and the future directions of the PHI-base project are briefly discussed.

Indexed as

Databases, GeneticComputational BiologyData CurationGenomicsHost-Pathogen InteractionsPhenotypeSearch EngineUser-Computer InterfaceWeb Browser

Identifiers

PMID27915230
PMCPMC5210566
OpenAlexW2560844000

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.