Evidence map›Paper›PMID 27914945›Full record

ArticlePharmacological research2017

Effects of zacopride, a moderate I

Mohammad T Elnakish, Benjamin D Canan, Ahmet Kilic, Peter J Mohler, Paul M L Janssen

Open access · greenAbstract read
In one paragraph

Article in Pharmacological research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 21 citations in OpenAlex.

  1. Prokinetic drugs that stimulate 5-HTNaunyn-Schmiedeberg's archives of pharmacology · 2026
    Review
  2. Article
  3. The network of cardiac KNaunyn-Schmiedeberg's archives of pharmacology · 2024
    Review
  4. Zacopride stimulates 5-HTNaunyn-Schmiedeberg's archives of pharmacology · 2024
    Article
  5. Cardiac Roles of Serotonin (5-HT) and 5-HT-Receptors in Health and Disease.International journal of molecular sciences · 2023
    Review
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Synchronization of Intracellular CaFrontiers in physiology · 2018
    Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 2 countries.

Mohammad T ElnakishDepartment of Physiology and Cell Biology, College of Medicine, The Ohio State University, USA; Dorothy M. Davis Heart & Lung Research Institute, The Ohio State University, Columbus, OH, USA; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Helwan University, Cairo, Egypt. Electronic address: elnakish.1@osu.edu.
Benjamin D CananDepartment of Physiology and Cell Biology, College of Medicine, The Ohio State University, USA; Dorothy M. Davis Heart & Lung Research Institute, The Ohio State University, Columbus, OH, USA.
Ahmet KilicDepartment of Surgery, Division of Cardiac Surgery, The Ohio State University, Wexner Medical Center, USA.
Peter J MohlerDepartment of Physiology and Cell Biology, College of Medicine, The Ohio State University, USA; Dorothy M. Davis Heart & Lung Research Institute, The Ohio State University, Columbus, OH, USA.
Paul M L JanssenDepartment of Physiology and Cell Biology, College of Medicine, The Ohio State University, USA; Dorothy M. Davis Heart & Lung Research Institute, The Ohio State University, Columbus, OH, USA. Electronic address: janssen.10@osu.edu.
Lung Institute · USHelwan University · EGThe Ohio State University · USThe Ohio State University Wexner Medical Center · US

Funding

Defining novel mechanisms for human arrhythmiaR35HL135754 · NHLBI · OHIO STATE UNIVERSITY · PI MOHLER, PETER J. · 2017 to 2023
$6.0M
Frequency-dependent modulation of cardiac myofilament function in health/diseaseR01HL113084 · NHLBI · OHIO STATE UNIVERSITY · PI JANSSEN, PAULUS ML · 2012 to 2023
$4.6M
NHLBI NIH HHS R01 HL113084NHLBI NIH HHS R35 HL135754
6 · The paper itself

Abstract

Ventricular tachycardia is the leading cause of sudden arrhythmic death in the U.S. Recently, the moderate I

Indexed as

AdultAnti-Arrhythmia AgentsArrhythmias, CardiacBenzamidesBridged Bicyclo Compounds, HeterocyclicFemaleHeart FailureHeart VentriclesHumansMaleMiddle AgedMyocardial ContractionMyocardiumMyocytes, CardiacPotassium Channels, Inwardly RectifyingSerotonin AntagonistsAnti-Arrhythmia AgentsBenzamidesBridged Bicyclo Compounds, HeterocyclicPotassium Channels, Inwardly RectifyingSerotonin AntagonistszacoprideContractilityHuman heartI(K1) channelTriggered arrhythmiaZacopride

Identifiers

PMID27914945
PMCPMC5234043
OpenAlexW2558094479

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.