ArticleJournal of the Academy of Nutrition and Dietetics2017
Physical Activity Modifies the Association between Dietary Protein and Lean Mass of Postmenopausal Women.
Article in Journal of the Academy of Nutrition and Dietetics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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The trial behind it
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Who cites it
7 citing papers in PubMed.
- Metabolic Changes of Perimenopause and Nutritional Advice.Current nutrition reports · 2026Review
- Estimating the effect of hypothetical dietary protein interventions on changes in body composition of postmenopausal women over 3 years using data from the Women's Health Initiative (WHI) Study: an emulated target trial.International journal of obesity (2005) · 2026Article
- Prevalence and Diagnostic Strategies for Sarcopenia in Menopausal and Non-Menopausal Women: A Cross-Sectional Comparative Study.International journal of women's health · 2025Article
- Commentary on the Women's Health Initiative: Over 30 Years of Contribution to Nutrition and Dietetics.Journal of the Academy of Nutrition and Dietetics · 2024Article
- Weight gain during the menopause transition: Evidence for a mechanism dependent on protein leverage.BJOG : an international journal of obstetrics and gynaecology · 2023Article
- A Priori Dietary Patterns, Physical Activity Level, and Body Composition in Postmenopausal Women: A Cross-Sectional Study.International journal of environmental research and public health · 2022Article
- The Relationships between Total Protein Intake, Protein Sources, Physical Activity, and Lean Mass in a Representative Sample of the US Adults.Nutrients · 2020Article
Corrections and comments
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Authors and funding
10 authors.
Funding
Abstract
backgroundMaintenance of lean muscle mass and related strength is associated with lower risk for numerous chronic diseases of aging in women.
objectiveOur aim was to evaluate whether the association between dietary protein and lean mass differs by physical activity level, amino acid composition, and body mass index categories.
designWe performed a cross-sectional analysis of a prospective cohort. PARTICIPANTS/
settingParticipants were postmenopausal women from the Women's Health Initiative with body composition measurements by dual-energy x-ray absorptiometry (n=8,298).
main outcome measuresOur study measured percent lean mass, percent fat mass, and lean body mass index. STATISTICAL ANALYSES PERFORMED: Linear regression models adjusted for scanner serial number, age, calibrated energy intake, race/ethnicity, neighborhood socioeconomic status, and recreational physical activity were used to determine the relationship between protein intake and body composition measures. Likelihood ratio tests and stratified analysis were used to investigate physical activity and body mass index as potential effect modifiers.
resultsBiomarker-calibrated protein intake was positively associated with percent lean mass; women in the highest protein quintile had 6.3 percentage points higher lean mass than the lowest quintile (P<0.001). This difference rose to 8.5 percentage points for physically active women in the highest protein quintile (P
conclusionsProtein consumption up to 2.02 g/kg body weight daily is positively associated with lean mass in postmenopausal women. Importantly, those that also engage in physical activity have the highest lean mass across body mass index categories.
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