ArticleJournal of the American Medical Directors Association2017
Falls, Cognitive Impairment, and Gait Performance: Results From the GOOD Initiative.
Article in Journal of the American Medical Directors Association, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 86 papers, 4 of them syntheses that pooled it.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
86 citing papers in PubMed, 4 syntheses or guidelines pooled it, 183 citations in OpenAlex.
- Prognostic factors for falls in Parkinson's disease: a systematic review.Acta neurologica Belgica · 2024Pooled it
- The Nebulous Association between Cognitive Impairment and Falls in Older Adults: A Systematic Review of the Literature.International journal of environmental research and public health · 2023Pooled it
- Fall prevention in community-dwelling adults with mild to moderate cognitive impairment: a systematic review and meta-analysis.BMC geriatrics · 2021Pooled it
- Pooled it
- Efficacy and safety of using auditory-motor entrainment to improve walking after stroke: a multi-site randomized controlled trial of InTandemNature communications · 2024Trial
- Implementing an Online Virtual Falls Prevention Intervention During a Public Health Pandemic for Older Adults with Mild Cognitive Impairment: A Feasibility Trial.Clinical interventions in aging · 2021Trial
- Factors associated with the risk of falls and their relationship with cognitive function in older adults with cognitive impairment: a cross-sectional study.GeroScience · 2026Article
- Dual-task versus single-task walking within an Otago Exercise Program for older adults with dementia: A 24-week cluster randomized controlled trial.Journal of exercise science and fitness · 2026Article
- Enhancing fall risk assessment in the oldest old: The interplay of cognition and gait speed.GeroScience · 2026Article
- The Usefulness of Falls Efficacy Scale-International in Predicting Falls in Chronic Kidney Disease Patients.Journal of clinical medicine · 2026Article
- Multimodal Integration of Gait Dysfunction, Amyloid PET, and Plasma Biomarkers for Differentiating Etiological Subtypes in Mild Cognitive Impairment.CNS neuroscience & therapeutics · 2026Article
- Article
- Identification and Evaluation of the Additional Effect of Cognitive Training in Balance Physiotherapy.Journal of frailty, sarcopenia and falls · 2026Review
- Nonlinear Gait Variability and the Role of Cognitive-Physical Exercise in Mitigating Mobility Decline in Institutionalized Older Adults with Cognitive Impairment.Journal of functional morphology and kinesiology · 2026Article
- Living Space Mobility and Liberty Deprivation Measures Among Residents With Dementia in Long-Term Inpatient Care: A Longitudinal Study.Nursing open · 2026Observational
- Gait and Dual-Task Performance in Older Adults with Suspected Cognitive Impairment: Effects of an 8-Week Exercise Program.Healthcare (Basel, Switzerland) · 2025Article
- Association between falls and dementia risk: Evidence from three cohort studies.Journal of translational internal medicine · 2025Article
- Evaluation of risk factors for falls among elderly patients attending a teaching hospital in southern Nigeria: a cross-sectional study.Scientific reports · 2025Article
- Safety, Cognitive, and Behavioral Outcomes in Patients with Dementia with Lewy Bodies Treated with Nilotinib.Journal of clinical medicine · 2025Article
- Association of motoric cognitive risk syndrome with falls in older adults: findings from three longitudinal studies.BMC geriatrics · 2025Article
26 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 9 institutions in 7 countries.
Funding
Abstract
objectivesFalls are highly prevalent in individuals with cognitive decline. The complex relationship between falls and cognitive decline (including both subtype and severity of dementia) and the influence of gait disorders have not been studied. This study aimed to examine the association between the subtype (Alzheimer disease [AD] versus non-AD) and the severity (from preclinical to moderate dementia) of cognitive impairment and falls, and to establish an association between falls and gait parameters during the course of dementia.
designMulticenter cross-sectional study.
setting"Gait, cOgnitiOn & Decline" (GOOD) initiative.
participantsA total of 2496 older adults (76.6 ± 7.6 years; 55.0% women) were included in this study (1161 cognitively healthy individuals [CHI], 529 patients with mild cognitive impairment [MCI], 456 patients with mild dementia, and 350 with moderate dementia) from 7 countries. MEASUREMENTS: Falls history was collected retrospectively at baseline in each study. Gait speed and stride time variability were recorded at usual walking pace with the GAITRite system.
resultsThe prevalence of individuals who fall was 50% in AD and 64% in non-AD; whereas it was 25% in CHIs. Only mild and moderate non-AD dementia were associated with an increased risk for falls in comparison with CHI. Higher stride time variability was associated with falls in older adults without dementia (CHI and each MCI subgroup) and mild non-AD dementia, whereas lower gait speed was associated with falls in all participant groups, except in mild AD dementia. When gait speed was adjusted for, higher stride time variability was associated with falls only in CHIs (odds ratio 1.14; P = .012), but not in MCI or in patients with dementia.
conclusionsThese findings suggest that non-AD, but not AD dementia, is associated with increased falls in comparison with CHIs. The association between gait parameters and falls also differs across cognitive status, suggesting different mechanisms leading to falls in older individuals with dementia in comparison with CHIs who fall.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.