Evidence map›Paper›PMID 27914647›Full record

ArticleThe Science of the total environment2017

Human exposure to dietary inorganic arsenic and other arsenic species: State of knowledge, gaps and uncertainties.

Francesco Cubadda, Brian P Jackson, Kathryn L Cottingham, Yoshira Ornelas Van Horne, Margaret Kurzius-Spencer

Abstract read
In one paragraph

Article in The Science of the total environment, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 79 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
79citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

79 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. The impact of environmental pollution on the quality of mother's milk.Environmental science and pollution research international · 2019
    Pooled it
  4. Pooled it
  5. Trial
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Review
  14. Biomonitoring of inorganic arsenic species in pregnancy.Journal of exposure science & environmental epidemiology · 2023
    Review
  15. Gene regulation and ionome homeostasis in rice plants in response to arsenite stress: potential connection between transcriptomics and ionomics.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2023
    Article
  16. Article
  17. Effect of Micro-Nanobubbles on Arsenic Removal byJournal of fungi (Basel, Switzerland) · 2023
    Article
  18. A review of mechanisms underlying the protective effects of natural compounds against arsenic-induced neurotoxicity.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2023
    Review
  19. Article
  20. Article

19 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Francesco CubaddaDepartment of Food Safety and Veterinary Public Health, Istituto Superiore di Sanità-Italian National Institute of Health, Rome, Italy. Electronic address: francesco.cubadda@iss.it.
Brian P JacksonDepartment of Earth Sciences, Dartmouth College, Hanover, NH, USA.
Kathryn L CottinghamDepartment of Biological Sciences, Dartmouth College, Hanover, NH, USA.
Yoshira Ornelas Van HorneDepartment of Community, Environment and Policy, University of Arizona, Tucson, AZ, USA.
Margaret Kurzius-SpencerDepartment of Community, Environment and Policy, University of Arizona, Tucson, AZ, USA.

Funding

VARIATION IN BIOACCUMULATION AND BIOMAGNIFICATION OF METALS IN NORTHERN US LAKESP42ES007373 · NIEHS · DARTMOUTH COLLEGE · PI STANTON, BRUCE A. · 1995 to 2019
$52.0M
SOUTHWEST ENVIRONMENTAL HEALTH SCIENCES CENTERP30ES006694 · NIEHS · UNIVERSITY OF ARIZONA · PI DEAN BILLHEIMER · 1994 to 2026
$36.7M
Training in Environmental Toxicology of Human DiseaseT32ES007091 · NIEHS · UNIVERSITY OF ARIZONA · PI Nathan J Cherrington · 1985 to 2026
$10.7M
Project 3: Placental Biomarkers of Exposure and Outcome (Marsit)P01ES022832 · NIEHS · DARTMOUTH COLLEGE · PI MURRAY, CAROLYN J · 2013 to 2018
$4.7M
Collaborative on Food with Arsenic and Associated Risk and RegulationR13ES026493 · NIEHS · DARTMOUTH COLLEGE · PI CHEN, CELIA Y · 2016 to 2016
$20k
NIEHS NIH HHS P01 ES022832NIEHS NIH HHS P30 ES006694NIEHS NIH HHS P42 ES007373NIEHS NIH HHS R13 ES026493NIEHS NIH HHS T32 ES007091
6 · The paper itself

Abstract

Inorganic arsenic (iAs) is ubiquitous in the environment as arsenite (AsIII) and arsenate (AsV) compounds and biotransformation of these toxic chemicals leads to the extraordinary variety of organoarsenic species found in nature. Despite classification as a human carcinogen based on data from populations exposed through contaminated drinking water, only recently has a need for regulatory limits on iAs in food been recognized. The delay was due to the difficulty in risk assessment of dietary iAs, which critically relies on speciation analysis providing occurrence data for iAs in food - and not simply for total arsenic. In the present review the state of knowledge regarding arsenic speciation in food and diet is evaluated with focus on iAs and human exposure assessment through different dietary approaches including duplicate diet studies, market basket surveys, and total diet studies. The analytical requirements for obtaining reliable data for iAs in food are discussed and iAs levels in foods and beverages are summarized, along with information on other (potentially) toxic co-occurring organoarsenic compounds. Quantitative exposure assessment of iAs in food is addressed, focusing on the need of capturing variability and extent of exposure and identifying what dietary items drive very high exposure for certain population groups. Finally, gaps and uncertainties are discussed, including effect of processing and cooking, and iAs bioavailability.

Indexed as

ArsenicDietDietary ExposureEnvironmental PollutantsEnvironmental PollutionFood ContaminationHumansRisk AssessmentArsenicEnvironmental PollutantsArsenic speciationDietary exposureFoodHuman healthInorganic arsenicRisk assessment

Identifiers

PMID27914647
PMCPMC5207036

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.