Evidence map›Paper›PMID 27914611›Full record

ArticleThe Kaohsiung journal of medical sciences2016

Restoration of uridine 5'-triphosphate-suppressed delayed rectifying K

Zen-Kong Dai, Chang-Ling Kao, Su-Ling Hsieh, Ing-Jun Chen, Bin-Nan Wu

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Kaohsiung journal of medical sciences, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Zen-Kong DaiDepartment of Pediatrics, Division of Pediatric Pulmonology and Cardiology, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan.
Chang-Ling KaoDepartment of Pharmacology, Graduate Institute of Medicine, College of Medicine, Lipid Science and Aging Research Center, Kaohsiung Medical University, Kaohsiung, Taiwan.
Su-Ling HsiehDepartment of Pharmacy, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan.
Ing-Jun ChenDepartment of Pharmacology, Graduate Institute of Medicine, College of Medicine, Lipid Science and Aging Research Center, Kaohsiung Medical University, Kaohsiung, Taiwan.
Bin-Nan WuDepartment of Pharmacology, Graduate Institute of Medicine, College of Medicine, Lipid Science and Aging Research Center, Kaohsiung Medical University, Kaohsiung, Taiwan. Electronic address: binnan@kmu.edu.tw.
Kaohsiung Medical University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We have demonstrated that KMUP-1 (7-[2-[4-(2-chlorobenzene)piperazinyl]ethyl]-1,3-dimethylxanthine) blunts monocrotaline-induced pulmonary arterial hypertension by altering Ca

Indexed as

4-AminopyridineAmidesAnimalsCalciumCytosolDelayed Rectifier Potassium ChannelsDown-RegulationFemaleIon Channel GatingMyocytes, Smooth MuscleNitric OxidePiperidinesPulmonary ArteryPyridinesRats, Sprague-DawleyrhoA GTP-Binding Protein4-AminopyridineAmidesCalciumDelayed Rectifier Potassium ChannelsKMUP 1Nitric OxidePiperidinesPyridinesrhoA GTP-Binding Proteinrho-Associated KinasesUridine TriphosphateXanthinesY 27632K(DR) channelsKMUP-1Patch-clamp electrophysiologyPulmonary artery smooth muscle cellsRhoA/ROCK signaling

Identifiers

PMID27914611
PMCPMC11916010
OpenAlexW2541928401

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.