ArticleHealth and quality of life outcomes2016
Impact of the occurrence of a response shift on the determination of the minimal important difference in a health-related quality of life score over time.
Article in Health and quality of life outcomes, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 4 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Impact of response shift on change in patient-reported outcomes: a systematic review.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2026Pooled it
- Comparison of adverse events in partial- or whole breast radiotherapy: investigation of cosmesis, toxicities and quality of life in a meta-analysis of randomized trials.Radiation oncology (London, England) · 2023Pooled it
- Pooled it
- The Role of Response-Shift in Studies Assessing Quality of Life Outcomes Among Cancer Patients: A Systematic Review.Frontiers in oncology · 2019Pooled it
- Development of a clinical decision support system for exercise prescription among cancer survivors: a modified Delphi study.Journal of cancer survivorship : research and practice · 2026Article
- Age-specific and time-dependent trends in health-related quality of life after minor stroke: results of a cross-sectional cohort study.BMJ neurology open · 2026Article
- Palliative care pathways in Amyotrophic Lateral Sclerosis (ALS): a sequence analysis of health claims data.BMC palliative care · 2025Article
- Calculating the minimally important difference for the FACT-E from esophageal cancer surgery to recovery using distribution-based methods.Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus · 2025Article
- Visual quality of life in NMOSD and MOGAD: profiles, dynamics and associations with ageing and vision.Journal of neurology · 2024Article
- Breast-cancer specific comprehensive archive of Patient-Reported Outcome Measures (PROMs) for clinical research and clinical practice in oncology: Results from the PRO4All project.Breast (Edinburgh, Scotland) · 2024Article
- Long-Term Patient-Reported Arm Symptoms in Breast Cancer Survivors.Annals of surgical oncology · 2024Article
- Does participation in therapeutic exercise programs after finishing oncology treatment still ensure an adequate health status for long-term breast cancer survivors? A ≥ 5 years follow-up study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023Observational
- Correlation between work productivity loss and EORTC QLQ-C30 and -BR23 domains from the MONALEESA-7 trial of premenopausal women with HR+/HER2- advanced breast cancer.Therapeutic advances in medical oncology · 2022Article
- Determining clinically important differences in health-related quality of life in older patients with cancer undergoing chemotherapy or surgery.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2019Article
- The minimal important difference of the Australian Pelvic Floor Questionnaire.International urogynecology journal · 2019Article
- Distribution- and anchor-based methods to determine the minimally important difference on patient-reported outcome questionnaires in oncology: a structured review.Health and quality of life outcomes · 2018Review
- Quality of life, problems, and needs of disease-free breast cancer survivors 5 years after diagnosis.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2018Article
- Assessing health status over time: impact of recall period and anchor question on the minimal clinically important difference of copd health status tools.Health and quality of life outcomes · 2018Article
- The patients' view: impact of the extent of resection, intraoperative imaging, and awake surgery on health-related quality of life in high-grade glioma patients-results of a multicenter cross-sectional study.Neurosurgical review · 2018Article
Corrections and comments
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Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAn important challenge of the longitudinal analysis of health-related quality of life (HRQOL) is the potential occurrence of a Response Shift (RS) effect. While the impact of RS effect on the longitudinal analysis of HRQOL has already been studied, few studies have been conducted on its impact on the determination of the Minimal Important Difference (MID). This study aims to investigate the impact of the RS effect on the determination of the MID over time for each scale of both EORTC QLQ-C30 and QLQ-BR23 questionnaires in breast cancer patients.
methodsPatients with breast cancer completed the EORTC QLQ-C30 and the EORTC QLQ-BR23 questionnaires at baseline (time of diagnosis; T0), three months (T1) and six months after surgery (T2). Four hospitals and care centers participated in this study: cancer centers of Dijon and Nancy, the university hospitals of Reims and Strasbourg At T1 and T2, patients were asked to evaluate their HRQOL change during the last 3 months using the Jaeschke transition question. They were also asked to assess retrospectively their HRQOL level of three months ago. The occurrence of the RS effect was explored using the then-test method and its impact on the determination of the MID by using the Anchor-based method.
resultsBetween February 2006 and February 2008, 381 patients were included of mean age 58 years old (SD = 11). For patients who reported a deterioration of their HRQOL level at each follow-up, an increase of RS effect has been detected between T1 and T2 in 13/15 dimensions of QLQ-C30 questionnaire, and 4/7 dimensions of QLQ-BR23 questionnaire. In contrast, a decrease of the RS effect was observed in 8/15 dimensions of QLQ-C30 questionnaire and in 5/7 dimensions of QLQ-BR23 questionnaire in case of improvement. At T2, the MID became ≥ 5 points when taking into account the RS effect in 10/15 dimensions of QLQ-C30 questionnaire and in 5/7 dimensions of QLQ-BR23 questionnaire.
conclusionsThis study highlights that the RS effect increases over time in case of deterioration and decreases in case of improvement. Moreover, taking the RS into account produces a reliable and significant MID.
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