Evidence map›Paper›PMID 27914035›Full record

ArticleStem cell reviews and reports2017

Mobilization of Peripheral Blood Stem Cells and Changes in the Concentration of Plasma Factors Influencing their Movement in Patients with Panic Disorder.

Marcin Jabłoński, Jolanta Kucharska Mazur, Maciej Tarnowski, Barbara Dołęgowska, Daniel Pędziwiatr, Ewa Kubiś, Marta Budkowska, Daria Sałata, Justyna Pełka Wysiecka, Arkadiusz Kazimierczak and 3 more

Open access · hybridAbstract read
In one paragraph

Article in Stem cell reviews and reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 16 citations in OpenAlex.

  1. Trial
  2. Generation of Enucleated Erythrocytes From LinStem cells international · 2025
    Article
  3. The Relationship between the Lifestyle of the Allogeneic Stem Cell Donors and the Number of Donated CD34International journal of hematology-oncology and stem cell research · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 2 countries.

Marcin JabłońskiDepartment of Psychiatry, Pomeranian University of Medicine, Broniewskiego 26, 71-460, Szczecin, Poland.
Jolanta Kucharska MazurDepartment of Psychiatry, Pomeranian University of Medicine, Broniewskiego 26, 71-460, Szczecin, Poland. jola_kucharska@tlen.pl.
Maciej TarnowskiDepartment of Physiology, Pomeranian University of Medicine, Szczecin, Poland.
Barbara DołęgowskaDepartment of Medical Analytics, Pomeranian University of Medicine, Szczecin, Poland.
Daniel PędziwiatrDepartment of Physiology, Pomeranian University of Medicine, Szczecin, Poland.
Ewa KubiśDepartment of Physiology, Pomeranian University of Medicine, Szczecin, Poland.
Marta BudkowskaDepartment of Medical Analytics, Pomeranian University of Medicine, Szczecin, Poland.
Daria SałataDepartment of Medical Analytics, Pomeranian University of Medicine, Szczecin, Poland.
Justyna Pełka WysieckaDepartment of Psychiatry, Pomeranian University of Medicine, Broniewskiego 26, 71-460, Szczecin, Poland.
Arkadiusz KazimierczakDepartment of Vascular Surgery, Pomeranian University of Medicine, Szczecin, Poland.
Artur ReginiaDepartment of Psychiatry, Pomeranian University of Medicine, Broniewskiego 26, 71-460, Szczecin, Poland.
Mariusz Z RatajczakStem Cell Biology Program at the James Graham Brown Cancer Center, University of Louisville, Louisville, KY, 40202, USA.
Jerzy SamochowiecDepartment of Psychiatry, Pomeranian University of Medicine, Broniewskiego 26, 71-460, Szczecin, Poland.
Pomeranian Medical University · PLUniversity of Louisville · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this paper we examined whether stem cells and factors responsible for their movement may serve as new biological markers of anxiety disorders. The study was carried out on a group of 30 patients diagnosed with panic disorder (examined before and after treatment), compared to 30 healthy individuals forming the control group. We examined the number of circulating HSCs (hematopoetic stem cells) (Lin-/CD45 +/CD34 +) and HSCs (Lin-/CD45 +/AC133 +), the number of circulating VSELs (very small embryonic-like stem cells) (Lin-/CD45-/CD34 +) and VSELs (Lin-/CD45-/AC133 +), as well as the concentration of complement components: C3a, C5a and C5b-9, SDF-1 (stromal derived factor) and S1P (sphingosine-1-phosphate). Significantly lower levels of HSCs (Lin-/CD45 +/AC133 +) have been demonstrated in the patient group compared to the control group both before and after treatment. The level of VSELs (Lin-/CD45-/CD133 +) was significantly lower in the patient group before treatment as compared to the patient group after treatment.The levels of factors responsible for stem cell movement were significantly lower in the patient group compared to the control group before and after treatment. It was concluded that the study of stem cells and factors associated with their movement can be useful in the diagnostics of panic disorder, as well as differentiating between psychotic and anxiety disorders.

Indexed as

Cell MovementHematopoietic Stem Cell MobilizationAC133 AntigenAdultAntigens, CD34Anxiety DisordersCell CountChemokine CXCL12Complement System ProteinsFemaleFlow CytometryHumansLeukocyte Common AntigensMaleMiddle AgedPanic DisorderAC133 AntigenAntigens, CD34Chemokine CXCL12Complement System ProteinsCXCL12 protein, humanLeukocyte Common AntigensPROM1 protein, humanComplement componentsPanic disorderSDF-1Sphingosine - 1 – phosphateStem cellsVSEL

Identifiers

PMID27914035
PMCPMC5380702
OpenAlexW2558402651

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.