Evidence map›Paper›PMID 27913995›Full record

Trial reportDigestive diseases and sciences2017

Adenoma Prevalence and Distribution Among US Latino Subgroups Undergoing Screening Colonoscopy.

Sumedha V Chablani, Lina Jandorf, Katherine DuHamel, Kristen K Lee, Pathu Sriphanlop, Cristina Villagra, Steven H Itzkowitz

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Digestive diseases and sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Sumedha V ChablaniUPMC Montefiore Hospital, N715, 200 Lothrop Street, Pittsburgh, PA, 15213, USA. svchablani@gmail.com.
Lina JandorfIcahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, Box 1130, New York, NY, 10029, USA.
Katherine DuHamelDepartment of Psychiatry, Memorial Sloan Kettering Cancer Center, 641 Lexington Avenue, 7th Floor, New York, NY, 10022, USA.
Kristen K LeeDigestive Healthcare Center, 511 Courtyard Drive, Building 500, Hillsborough, NJ, 08844, USA.
Pathu SriphanlopIcahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, Box 1130, New York, NY, 10029, USA.
Cristina VillagraIcahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, Box 1130, New York, NY, 10029, USA.
Steven H ItzkowitzIcahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, Box 1069, New York, NY, 10029, USA.
Icahn School of Medicine at Mount Sinai · USDigestive Care (United States) · USUPMC Montefiore · US

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Hongbiao Carl Lekaye · 1985 to 2026
$347.4M
Improving CRC Screening for Diverse Hispanics in an Urban Primary Care SettingR01CA140737 · NCI · SLOAN-KETTERING INST CAN RESEARCH · PI DUHAMEL, KATHERINE N · 2011 to 2014
$2.5M
NCI NIH HHS P30 CA008748NCI NIH HHS R01 CA140737
6 · The paper itself

Abstract

backgroundColorectal cancer (CRC) is the second leading malignancy diagnosed among US Latinos. Latinos in the USA represent a heterogeneous amalgam of subgroups varying in genetic background, culture, and socioeconomic status. Little is known about the frequency of CRC precursor lesions found at screening colonoscopy among Latino subgroups.

aimThe aim was to determine the prevalence and distribution of histologically confirmed adenomas found at screening colonoscopy among average-risk, asymptomatic US Latinos according to their subgroup and socio-demographic background.

methodsCross-sectional analysis of pathological findings resulting from screening colonoscopy among average-risk, asymptomatic US Latinos aged ≥50 in two prospective randomized controlled trials at an academic medical center.

resultsAmong the 561 Latinos who completed screening colonoscopy, the two largest subgroups were Puerto Ricans and Dominicans. The findings among both subgroups were: adenomas 30.6%, proximal adenomas 23.5%, advanced adenomas 12.0%, and proximal advanced adenomas 8.9%. These rates are at least as high as those found at screening colonoscopy among US whites. While Puerto Ricans were more likely than Dominicans to be born in the USA, speak English, be acculturated, have a smoking history, and be obese, there were no significant differences in adenoma rates between these subgroups.

conclusionsThe prevalence of adenomas, advanced adenomas, and proximal neoplasia was high among both subgroups. These findings have implications for CRC screening and surveillance among the increasingly growing Latino population in the USA.

Indexed as

AcculturationAdenomaAgedAge FactorsColonoscopyColorectal NeoplasmsCross-Sectional StudiesDominican RepublicEarly Detection of CancerEmigration and ImmigrationFemaleHispanic or LatinoHumansMaleMiddle AgedPrevalenceAdenomaColonoscopyColorectal cancerLatinosScreening

Identifiers

PMID27913995
PMCPMC5731829
OpenAlexW2557963729

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.