ArticleLasers in medical science2017
Laser photobiomodulation (830 and 660 nm) in mast cells, VEGF, FGF, and CD34 of the musculocutaneous flap in rats submitted to nicotine.
Article in Lasers in medical science, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.
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Who cites it
25 citing papers in PubMed, 1 synthesis or guideline pooled it, 41 citations in OpenAlex.
- Photobiomodulation in promoting increased Skin Flap Viability: a systematic review of animal studies.Lasers in medical science · 2024Pooled it
- Short-Term Nicotine Improves Experimental Flap Survival: Implications for Different Findings in Experimental Flap Models.Medicina (Kaunas, Lithuania) · 2026Article
- Photobiomodulation at 830 nm with 5 J/cmLasers in medical science · 2026Article
- Photobiomodulation and Low-Level Laser Therapy as Complementary Strategies in Diabetes Treatment.International journal of molecular sciences · 2026Review
- Number of sessions of applications of laser photobiomodulation therapy interferes with the viability of skin flap: an experimental study in rats.Lasers in medical science · 2025Article
- Does Preconditioning with Transcutaneous Electrical Nerve Stimulation (TENS) Increase Transverse Rectus Abdominis Musculocutaneous (TRAM) Flap Viability? An Experimental Rat Model Study.Journal of clinical practice and research · 2025Article
- Photobiomodulation (100 mW) caution applied to tattooed skin: a cross-sectional study.Archives of dermatological research · 2025Article
- In vivo attenuation profile of 660 nm and 830 nm wavelengths on human elbow skin and calcaneus tendon of different phototypes.Lasers in medical science · 2024Article
- Low-Level Laser Therapy Induces Melanoma Tumor Growth by Promoting Angiogenesis.Life (Basel, Switzerland) · 2023Article
- Expression and degranulation of mast cells in laser photobiomodulated mucositis chemo-induced: pilot study in hamsters.Lasers in medical science · 2023Article
- Activation of Wnt/β-Catenin Signaling Involves 660 nm Laser Radiation on Epithelium and Modulates Lipid Metabolism.Biomolecules · 2022Article
- Viability of transverse rectus abdominis musculocutaneous flap treated with photobiomodulation and therapeutic ultrasound: an experimental model.Lasers in medical science · 2022Article
- Photobiomodulation therapy was more effective than photobiomodulation plus arginine on accelerating wound healing in an animal model of delayed healing wound.Lasers in medical science · 2022Article
- Comparison of photobiomodulation in the treatment of skin injury with an open wound in mice.Lasers in medical science · 2021Article
- Microglia modulation with 1070-nm light attenuates Aβ burden and cognitive impairment in Alzheimer's disease mouse model.Light, science & applications · 2021Article
- Electric Factors in Wound Healing.Advances in wound care · 2021Article
- Effects of photobiomodulation therapy on functional recovery, angiogenesis and redox status in denervated muscle of rats.Einstein (Sao Paulo, Brazil) · 2021Article
- In vitro effects of photobiomodulation applied to gingival fibroblasts cultured on titanium and zirconia surfaces and exposed to LPS from Escherichia coli.Lasers in medical science · 2020Article
- Physical exercise and low-level laser therapy on the nociception and leukocyte migration of Wistar rats submitted to a model of rheumatoid arthritis.Lasers in medical science · 2020Article
- Effects of photobiomodulation therapy in the integration of skin graft in rats.Lasers in medical science · 2020Article
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The aim of this study was to investigate the effect of laser photobiomodulation (PBM) on the viability of the transverse rectus abdominis musculocutaneous (TRAM) flap in rats subjected to the action of nicotine. We evaluated 60 albino Wistar rats, divided into six groups of ten animals. Group 1 (saline) underwent the surgical technique to obtain a TRAM flap; group 2 (laser 830 nm) underwent the surgical technique and was irradiated with a laser 830 nm; group 3 (laser 660 nm) underwent the surgical technique and was irradiated with a laser 660 nm; group 4 was treated with nicotine subcutaneously (2 mg/kg/2×/day/4 weeks) and underwent surgery; group 5 (nicotine + laser 830 nm) was exposed to nicotine, underwent the surgical technique, and was irradiated with a laser 830 nm; group 6 (nicotine + laser 660 nm) was exposed to nicotine, underwent the surgical technique, and was irradiated with a laser 660 nm. The application of PBM occurred immediately after surgery and on the two following days. The percentage of necrosis was assessed using the AxioVision® software. The number of mast cells (toluidine blue staining) was evaluated, and immunohistochemistry was performed to detect vascular endothelial growth factor expression (anti-VEGF-A), fibroblasts (anti-basic FGF), and neoformed vessels (anti-CD34). PBM with a wavelength of 830 nm increased the viability of the TRAM flap, with a smaller area of necrosis, increased number of mast cells, and higher expression of VEGF and CD34. PBM increases the viability of musculocutaneous flaps treated with to nicotine.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.