Evidence map›Paper›PMID 27913959›Full record

ArticleJournal of neurovirology2017

Reaction of complement factors and proteasomes in experimental encephalitis.

Stefan Lange, Tomas Bergström, Ewa Johansson, Merna Oshalim, Ivar Lönnroth

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of neurovirology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.2field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Stefan LangeDepartment of Infectious Diseases, Institute of Biomedicine, Gothenburg University, P.O.B 420, S-40530, Gothenburg, Sweden.
Tomas BergströmDepartment of Infectious Diseases, Institute of Biomedicine, Gothenburg University, P.O.B 420, S-40530, Gothenburg, Sweden.
Ewa JohanssonDepartment of Infectious Diseases, Institute of Biomedicine, Gothenburg University, P.O.B 420, S-40530, Gothenburg, Sweden.
Merna OshalimDepartment of Infectious Diseases, Institute of Biomedicine, Gothenburg University, P.O.B 420, S-40530, Gothenburg, Sweden.
Ivar LönnrothDepartment of Infectious Diseases, Institute of Biomedicine, Gothenburg University, P.O.B 420, S-40530, Gothenburg, Sweden. Ivar.Lonnroth@microbio.gu.se.
Sahlgrenska University Hospital · SEUniversity of Gothenburg · SEInstitute for Biomedicine · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Herpes simplex virus type 1 (HSV-1) encephalitis causes a deleterious inflammation and elevated intracranial pressure. As a step towards examining the origin of the inflammation, we here report the response of circulating proteasomes and complement factors in blood and cerebrospinal fluid (CSF) in rats infected with HSV-1. Infection was via the nasal route, with 1.1 × 10

Indexed as

Adenosine TriphosphateAdministration, IntranasalAnimalsComplement System ProteinsDisease Models, AnimalEnzyme-Linked Immunosorbent AssayHerpes SimplexHerpesvirus 1, HumanHumansMaleProteasome Endopeptidase ComplexProtein BindingRatsRats, Sprague-DawleyAdenosine TriphosphateATP dependent 26S proteaseComplement System ProteinsProteasome Endopeptidase ComplexCompleasomeComplement factorEncephalitisHerpes simplex virus type 1Proteasome

Identifiers

PMID27913959
PMCPMC5332498
OpenAlexW2557985811

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.